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128 results

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Page 1
Inhaled anesthetic responses of recombinant receptors and knockin mice harboring α2(S270H/L277A) GABA(A) receptor subunits that are resistant to isoflurane.
Werner DF, Swihart A, Rau V, Jia F, Borghese CM, McCracken ML, Iyer S, Fanselow MS, Oh I, Sonner JM, Eger EI 2nd, Harrison NL, Harris RA, Homanics GE. Werner DF, et al. J Pharmacol Exp Ther. 2011 Jan;336(1):134-44. doi: 10.1124/jpet.110.170431. Epub 2010 Aug 31. J Pharmacol Exp Ther. 2011. PMID: 20807777 Free PMC article.
An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice.
Borghese CM, Werner DF, Topf N, Baron NV, Henderson LA, Boehm SL 2nd, Blednov YA, Saad A, Dai S, Pearce RA, Harris RA, Homanics GE, Harrison NL. Borghese CM, et al. Among authors: werner df. J Pharmacol Exp Ther. 2006 Oct;319(1):208-18. doi: 10.1124/jpet.106.104406. Epub 2006 Jun 28. J Pharmacol Exp Ther. 2006. PMID: 16807363
GABAA receptor alpha 4 subunits mediate extrasynaptic inhibition in thalamus and dentate gyrus and the action of gaboxadol.
Chandra D, Jia F, Liang J, Peng Z, Suryanarayanan A, Werner DF, Spigelman I, Houser CR, Olsen RW, Harrison NL, Homanics GE. Chandra D, et al. Among authors: werner df. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15230-5. doi: 10.1073/pnas.0604304103. Epub 2006 Sep 27. Proc Natl Acad Sci U S A. 2006. PMID: 17005728 Free PMC article.
Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane.
Sonner JM, Werner DF, Elsen FP, Xing Y, Liao M, Harris RA, Harrison NL, Fanselow MS, Eger EI 2nd, Homanics GE. Sonner JM, et al. Among authors: werner df. Anesthesiology. 2007 Jan;106(1):107-13. doi: 10.1097/00000542-200701000-00019. Anesthesiology. 2007. PMID: 17197852
Isoflurane depression of spinal nociceptive processing and minimum alveolar anesthetic concentration are not attenuated in mice expressing isoflurane resistant gamma-aminobutyric acid type-A receptors.
Kim J, Atherley R, Werner DF, Homanics GE, Carstens E, Antognini JF. Kim J, et al. Among authors: werner df. Neurosci Lett. 2007 Jun 15;420(3):209-12. doi: 10.1016/j.neulet.2007.04.057. Epub 2007 Apr 29. Neurosci Lett. 2007. PMID: 17543455 Free PMC article.
Knockin mice with ethanol-insensitive alpha1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol.
Werner DF, Blednov YA, Ariwodola OJ, Silberman Y, Logan E, Berry RB, Borghese CM, Matthews DB, Weiner JL, Harrison NL, Harris RA, Homanics GE. Werner DF, et al. J Pharmacol Exp Ther. 2006 Oct;319(1):219-27. doi: 10.1124/jpet.106.106161. Epub 2006 Jun 19. J Pharmacol Exp Ther. 2006. PMID: 16785315
128 results