Castoldi E - Search Results

1

Protein S levels modulate the activated protein C resistance phenotype induced by elevated prothrombin levels.

Brugge JM, Tans G, Rosing J, Castoldi E. Brugge JM, et al. Among authors: castoldi e. Thromb Haemost. 2006 Feb;95(2):236-42. doi: 10.1160/TH05-08-0582. Thromb Haemost. 2006. PMID: 16493484

2

Molecular bases of pseudo-homozygous APC resistance: the compound heterozygosity for FV R506Q and a FV null mutation results in the exclusive presence of FV Leiden molecules in plasma.

Castoldi E, Kalafatis M, Lunghi B, Simioni P, Ioannou PA, Petio M, Girolami A, Mann KG, Bernardi F. Castoldi E, et al. Thromb Haemost. 1998 Sep;80(3):403-6. Thromb Haemost. 1998. PMID: 9759618

3

Mutations in the R2 FV gene affect the ratio between the two FV isoforms in plasma.

Castoldi E, Rosing J, Girelli D, Hoekema L, Lunghi B, Mingozzi F, Ferraresi P, Friso S, Corrocher R, Tans G, Bernardi F. Castoldi E, et al. Thromb Haemost. 2000 Mar;83(3):362-5. Thromb Haemost. 2000. PMID: 10744138

4

Functional properties of factor V and factor Va encoded by the R2-gene.

Hoekema L, Castoldi E, Tans G, Girelli D, Gemmati D, Bernardi F, Rosing J. Hoekema L, et al. Among authors: castoldi e. Thromb Haemost. 2001 Jan;85(1):75-81. Thromb Haemost. 2001. PMID: 11204592

5

Reduced factor V concentration and altered FV1/FV2 ratio do not fully explain R2-associated APC-resistance.

Govers-Riemslag JW, Castoldi E, Nicolaes GA, Tans G, Rosing J. Govers-Riemslag JW, et al. Among authors: castoldi e. Thromb Haemost. 2002 Sep;88(3):444-9. Thromb Haemost. 2002. PMID: 12353074

6

Coinheritance of Factor V (FV) Leiden enhances thrombin formation and is associated with a mild bleeding phenotype in patients homozygous for the FVII 9726+5G>A (FVII Lazio) mutation.

Castoldi E, Govers-Riemslag JW, Pinotti M, Bindini D, Tans G, Berrettini M, Mazzucconi MG, Bernardi F, Rosing J. Castoldi E, et al. Blood. 2003 Dec 1;102(12):4014-20. doi: 10.1182/blood-2003-04-1199. Epub 2003 Jul 24. Blood. 2003. PMID: 12881304 Free article.

7

Endogenous factor V synthesis in megakaryocytes contributes negligibly to the platelet factor V pool.

Thomassen MC, Castoldi E, Tans G, Magdeleyns EJ, Delaunoit C, Debusscher L, Van Assche KJ, Rosing J. Thomassen MC, et al. Among authors: castoldi e. Haematologica. 2003 Oct;88(10):1150-6. Haematologica. 2003. PMID: 14555311

8

Impaired APC cofactor activity of factor V plays a major role in the APC resistance associated with the factor V Leiden (R506Q) and R2 (H1299R) mutations.

Castoldi E, Brugge JM, Nicolaes GA, Girelli D, Tans G, Rosing J. Castoldi E, et al. Blood. 2004 Jun 1;103(11):4173-9. doi: 10.1182/blood-2003-10-3578. Epub 2004 Feb 19. Blood. 2004. PMID: 14976057 Free article.

9

Factor V Leiden: a disorder of factor V anticoagulant function.

Castoldi E, Rosing J. Castoldi E, et al. Curr Opin Hematol. 2004 May;11(3):176-81. doi: 10.1097/01.moh.0000130315.41033.32. Curr Opin Hematol. 2004. PMID: 15257017 Review.

10

An underestimated combination of opposites resulting in enhanced thrombotic tendency.

Simioni P, Castoldi E, Lunghi B, Tormene D, Rosing J, Bernardi F. Simioni P, et al. Among authors: castoldi e. Blood. 2005 Oct 1;106(7):2363-5. doi: 10.1182/blood-2005-04-1461. Epub 2005 Jun 16. Blood. 2005. PMID: 15961511 Free article.

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