Hartley JA - Search Results

1

Interaction of the epidermal growth factor receptor and the DNA-dependent protein kinase pathway following gefitinib treatment.

Friedmann BJ, Caplin M, Savic B, Shah T, Lord CJ, Ashworth A, Hartley JA, Hochhauser D. Friedmann BJ, et al. Among authors: hartley ja. Mol Cancer Ther. 2006 Feb;5(2):209-18. doi: 10.1158/1535-7163.MCT-05-0239. Mol Cancer Ther. 2006. PMID: 16505093 Free article.

2

DNA repair capacity and cisplatin sensitivity of human testis tumour cells.

Köberle B, Grimaldi KA, Sunters A, Hartley JA, Kelland LR, Masters JR. Köberle B, et al. Among authors: hartley ja. Int J Cancer. 1997 Mar 4;70(5):551-5. doi: 10.1002/(sici)1097-0215(19970304)70:5<551::aid-ijc10>3.0.co;2-g. Int J Cancer. 1997. PMID: 9052754

3

Effects of wild-type p53 expression on the quantity and activity of topoisomerase IIalpha and beta in various human cancer cell lines.

Hochhauser D, Valkov NI, Gump JL, Wei I, O'Hare C, Hartley J, Fan J, Bertino JR, Banerjee D, Sullivan DM. Hochhauser D, et al. J Cell Biochem. 1999 Nov 1;75(2):245-57. doi: 10.1002/(sici)1097-4644(19991101)75:2<245::aid-jcb7>3.3.co;2-7. J Cell Biochem. 1999. PMID: 10502297

4

Transcriptional regulation of topoisomerase II alpha at confluence and pharmacological modulation of expression by bis-benzimidazole drugs.

Tolner B, Hartley JA, Hochhauser D. Tolner B, et al. Among authors: hartley ja. Mol Pharmacol. 2001 Apr;59(4):699-706. doi: 10.1124/mol.59.4.699. Mol Pharmacol. 2001. PMID: 11259613

5

Measurement of the critical DNA lesions produced by antibody-directed enzyme prodrug therapy (ADEPT) in vitro, in vivo and in clinical material.

Webley SD, Francis RJ, Pedley RB, Sharma SK, Begent RH, Hartley JA, Hochhauser D. Webley SD, et al. Among authors: hartley ja. Br J Cancer. 2001 Jun 15;84(12):1671-6. doi: 10.1054/bjoc.2001.1843. Br J Cancer. 2001. PMID: 11401322 Free PMC article.

6

Repair of DNA interstrand crosslinks as a mechanism of clinical resistance to melphalan in multiple myeloma.

Spanswick VJ, Craddock C, Sekhar M, Mahendra P, Shankaranarayana P, Hughes RG, Hochhauser D, Hartley JA. Spanswick VJ, et al. Among authors: hartley ja. Blood. 2002 Jul 1;100(1):224-9. doi: 10.1182/blood.v100.1.224. Blood. 2002. PMID: 12070031 Free article.

7

SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activity.

Hartley JA, Spanswick VJ, Brooks N, Clingen PH, McHugh PJ, Hochhauser D, Pedley RB, Kelland LR, Alley MC, Schultz R, Hollingshead MG, Schweikart KM, Tomaszewski JE, Sausville EA, Gregson SJ, Howard PW, Thurston DE. Hartley JA, et al. Cancer Res. 2004 Sep 15;64(18):6693-9. doi: 10.1158/0008-5472.CAN-03-2941. Cancer Res. 2004. PMID: 15374986

8

Modulation of DNA repair in vitro after treatment with chemotherapeutic agents by the epidermal growth factor receptor inhibitor gefitinib (ZD1839).

Friedmann B, Caplin M, Hartley JA, Hochhauser D. Friedmann B, et al. Among authors: hartley ja. Clin Cancer Res. 2004 Oct 1;10(19):6476-86. doi: 10.1158/1078-0432.CCR-04-0586. Clin Cancer Res. 2004. PMID: 15475435

9

Assessment of the significance of mitochondrial DNA damage by chemotherapeutic agents.

Lo S, Tolner B, Taanman JW, Cooper JM, Gu M, Hartley JA, Schapira AH, Hochhauser D. Lo S, et al. Among authors: hartley ja. Int J Oncol. 2005 Aug;27(2):337-44. Int J Oncol. 2005. PMID: 16010413

10

Time-dependent cytotoxicity induced by SJG-136 (NSC 694501): influence of the rate of interstrand cross-link formation on DNA damage signaling.

Arnould S, Spanswick VJ, Macpherson JS, Hartley JA, Thurston DE, Jodrell DI, Guichard SM. Arnould S, et al. Among authors: hartley ja. Mol Cancer Ther. 2006 Jun;5(6):1602-9. doi: 10.1158/1535-7163.MCT-06-0018. Mol Cancer Ther. 2006. PMID: 16818520

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