Ojala PM - Search Results

1

Phosphorylation of the cyclin-dependent kinase inhibitor p21Cip1 on serine 130 is essential for viral cyclin-mediated bypass of a p21Cip1-imposed G1 arrest.

Järviluoma A, Child ES, Sarek G, Sirimongkolkasem P, Peters G, Ojala PM, Mann DJ. Järviluoma A, et al. Among authors: ojala pm. Mol Cell Biol. 2006 Mar;26(6):2430-40. doi: 10.1128/MCB.26.6.2430-2440.2006. Mol Cell Biol. 2006. PMID: 16508017 Free PMC article.

2

Kaposi's sarcoma-associated herpesvirus-encoded v-cyclin triggers apoptosis in cells with high levels of cyclin-dependent kinase 6.

Ojala PM, Tiainen M, Salven P, Veikkola T, Castaños-Vélez E, Sarid R, Biberfeld P, Mäkelä TP. Ojala PM, et al. Cancer Res. 1999 Oct 1;59(19):4984-9. Cancer Res. 1999. PMID: 10519412

3

The apoptotic v-cyclin-CDK6 complex phosphorylates and inactivates Bcl-2.

Ojala PM, Yamamoto K, Castaños-Vélez E, Biberfeld P, Korsmeyer SJ, Mäkelä TP. Ojala PM, et al. Nat Cell Biol. 2000 Nov;2(11):819-25. doi: 10.1038/35041064. Nat Cell Biol. 2000. PMID: 11056537

4

CAK-independent activation of CDK6 by a viral cyclin.

Kaldis P, Ojala PM, Tong L, Mäkelä TP, Solomon MJ. Kaldis P, et al. Among authors: ojala pm. Mol Biol Cell. 2001 Dec;12(12):3987-99. doi: 10.1091/mbc.12.12.3987. Mol Biol Cell. 2001. PMID: 11739795 Free PMC article.

5

KSHV viral cyclin binds to p27KIP1 in primary effusion lymphomas.

Järviluoma A, Koopal S, Räsänen S, Mäkelä TP, Ojala PM. Järviluoma A, et al. Among authors: ojala pm. Blood. 2004 Nov 15;104(10):3349-54. doi: 10.1182/blood-2004-05-1798. Epub 2004 Jul 22. Blood. 2004. PMID: 15271792 Free article.

6

KSHV viral cyclin inactivates p27KIP1 through Ser10 and Thr187 phosphorylation in proliferating primary effusion lymphomas.

Sarek G, Järviluoma A, Ojala PM. Sarek G, et al. Among authors: ojala pm. Blood. 2006 Jan 15;107(2):725-32. doi: 10.1182/blood-2005-06-2534. Epub 2005 Sep 13. Blood. 2006. PMID: 16160006 Free article.

7

Cell signaling pathways engaged by KSHV.

Järviluoma A, Ojala PM. Järviluoma A, et al. Among authors: ojala pm. Biochim Biophys Acta. 2006 Aug;1766(1):140-58. doi: 10.1016/j.bbcan.2006.05.001. Epub 2006 May 19. Biochim Biophys Acta. 2006. PMID: 16828973 Review.

8

Reactivation of the p53 pathway as a treatment modality for KSHV-induced lymphomas.

Sarek G, Kurki S, Enbäck J, Iotzova G, Haas J, Laakkonen P, Laiho M, Ojala PM. Sarek G, et al. Among authors: ojala pm. J Clin Invest. 2007 Apr;117(4):1019-28. doi: 10.1172/JCI30945. Epub 2007 Mar 15. J Clin Invest. 2007. PMID: 17364023 Free PMC article.

9

p53 reactivation kills KSHV lymphomas efficiently in vitro and in vivo: new hope for treating aggressive viral lymphomas.

Sarek G, Ojala PM. Sarek G, et al. Among authors: ojala pm. Cell Cycle. 2007 Sep 15;6(18):2205-9. doi: 10.4161/cc.6.18.4730. Epub 2007 Jul 10. Cell Cycle. 2007. PMID: 17890905 Review.

10

Viral oncogene-induced DNA damage response is activated in Kaposi sarcoma tumorigenesis.

Koopal S, Furuhjelm JH, Järviluoma A, Jäämaa S, Pyakurel P, Pussinen C, Wirzenius M, Biberfeld P, Alitalo K, Laiho M, Ojala PM. Koopal S, et al. Among authors: ojala pm. PLoS Pathog. 2007 Sep 7;3(9):1348-60. doi: 10.1371/journal.ppat.0030140. PLoS Pathog. 2007. PMID: 17907806 Free PMC article.

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