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Phase 1 study of ABT-751, a novel microtubule inhibitor, in patients with refractory hematologic malignancies.
Yee KW, Hagey A, Verstovsek S, Cortes J, Garcia-Manero G, O'Brien SM, Faderl S, Thomas D, Wierda W, Kornblau S, Ferrajoli A, Albitar M, McKeegan E, Grimm DR, Mueller T, Holley-Shanks RR, Sahelijo L, Gordon GB, Kantarjian HM, Giles FJ. Yee KW, et al. Among authors: sahelijo l. Clin Cancer Res. 2005 Sep 15;11(18):6615-24. doi: 10.1158/1078-0432.CCR-05-0650. Clin Cancer Res. 2005. PMID: 16166440 Clinical Trial.
Preclinical discovery of candidate genes to guide pharmacogenetics during phase I development: the example of the novel anticancer agent ABT-751.
Innocenti F, Ramírez J, Obel J, Xiong J, Mirkov S, Chiu YL, Katz DA, Carr RA, Zhang W, Das S, Adjei A, Moyer AM, Chen PX, Krivoshik A, Medina D, Gordon GB, Ratain MJ, Sahelijo L, Weinshilboum RM, Fleming GF, Bhathena A. Innocenti F, et al. Among authors: sahelijo l. Pharmacogenet Genomics. 2013 Jul;23(7):374-81. doi: 10.1097/FPC.0b013e3283623e81. Pharmacogenet Genomics. 2013. PMID: 23670235 Free PMC article. Clinical Trial.
A novel 'social contract' - An attempt to harmonize a sponsor's exploratory research with a clinical study participant's data rights.
Mignon L, Doan K, Murphy M, Elder L, Yun C, Milton J, Sasaki S, Hart CE, Montenegro D, Allen N, Matar D, Ciofani D, Rigo F, Sahelijo L. Mignon L, et al. Among authors: sahelijo l. Contemp Clin Trials. 2022 Aug;119:106819. doi: 10.1016/j.cct.2022.106819. Epub 2022 Jun 9. Contemp Clin Trials. 2022. PMID: 35691489 Free article.