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Page 1
Intestinal ABCA1 directly contributes to HDL biogenesis in vivo.
Brunham LR, Kruit JK, Iqbal J, Fievet C, Timmins JM, Pape TD, Coburn BA, Bissada N, Staels B, Groen AK, Hussain MM, Parks JS, Kuipers F, Hayden MR. Brunham LR, et al. Among authors: parks js. J Clin Invest. 2006 Apr;116(4):1052-62. doi: 10.1172/JCI27352. Epub 2006 Mar 16. J Clin Invest. 2006. PMID: 16543947 Free PMC article.
Hepatic ATP-binding cassette transporter A1 is a key molecule in high-density lipoprotein cholesteryl ester metabolism in mice.
Singaraja RR, Stahmer B, Brundert M, Merkel M, Heeren J, Bissada N, Kang M, Timmins JM, Ramakrishnan R, Parks JS, Hayden MR, Rinninger F. Singaraja RR, et al. Among authors: parks js. Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1821-7. doi: 10.1161/01.ATV.0000229219.13757.a2. Epub 2006 May 25. Arterioscler Thromb Vasc Biol. 2006. PMID: 16728652
Both hepatic and extrahepatic ABCA1 have discrete and essential functions in the maintenance of plasma high-density lipoprotein cholesterol levels in vivo.
Singaraja RR, Van Eck M, Bissada N, Zimetti F, Collins HL, Hildebrand RB, Hayden A, Brunham LR, Kang MH, Fruchart JC, Van Berkel TJ, Parks JS, Staels B, Rothblat GH, Fiévet C, Hayden MR. Singaraja RR, et al. Among authors: parks js. Circulation. 2006 Sep 19;114(12):1301-9. doi: 10.1161/CIRCULATIONAHA.106.621433. Epub 2006 Aug 28. Circulation. 2006. PMID: 16940190
Tissue-specific roles of ABCA1 influence susceptibility to atherosclerosis.
Brunham LR, Singaraja RR, Duong M, Timmins JM, Fievet C, Bissada N, Kang MH, Samra A, Fruchart JC, McManus B, Staels B, Parks JS, Hayden MR. Brunham LR, et al. Among authors: parks js. Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):548-54. doi: 10.1161/ATVBAHA.108.182303. Epub 2009 Feb 5. Arterioscler Thromb Vasc Biol. 2009. PMID: 19201688
Specific loss of brain ABCA1 increases brain cholesterol uptake and influences neuronal structure and function.
Karasinska JM, Rinninger F, Lütjohann D, Ruddle P, Franciosi S, Kruit JK, Singaraja RR, Hirsch-Reinshagen V, Fan J, Brunham LR, Bissada N, Ramakrishnan R, Wellington CL, Parks JS, Hayden MR. Karasinska JM, et al. Among authors: parks js. J Neurosci. 2009 Mar 18;29(11):3579-89. doi: 10.1523/JNEUROSCI.4741-08.2009. J Neurosci. 2009. PMID: 19295162 Free PMC article.
308 results