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Intestinal ABCA1 directly contributes to HDL biogenesis in vivo.
Brunham LR, Kruit JK, Iqbal J, Fievet C, Timmins JM, Pape TD, Coburn BA, Bissada N, Staels B, Groen AK, Hussain MM, Parks JS, Kuipers F, Hayden MR. Brunham LR, et al. Among authors: staels b. J Clin Invest. 2006 Apr;116(4):1052-62. doi: 10.1172/JCI27352. Epub 2006 Mar 16. J Clin Invest. 2006. PMID: 16543947 Free PMC article.
Human ABCA1 BAC transgenic mice show increased high density lipoprotein cholesterol and ApoAI-dependent efflux stimulated by an internal promoter containing liver X receptor response elements in intron 1.
Singaraja RR, Bocher V, James ER, Clee SM, Zhang LH, Leavitt BR, Tan B, Brooks-Wilson A, Kwok A, Bissada N, Yang YZ, Liu G, Tafuri SR, Fievet C, Wellington CL, Staels B, Hayden MR. Singaraja RR, et al. Among authors: staels b. J Biol Chem. 2001 Sep 7;276(36):33969-79. doi: 10.1074/jbc.M102503200. Epub 2001 Jun 21. J Biol Chem. 2001. PMID: 11423537 Free article.
Increased ABCA1 activity protects against atherosclerosis.
Singaraja RR, Fievet C, Castro G, James ER, Hennuyer N, Clee SM, Bissada N, Choy JC, Fruchart JC, McManus BM, Staels B, Hayden MR. Singaraja RR, et al. Among authors: staels b. J Clin Invest. 2002 Jul;110(1):35-42. doi: 10.1172/JCI15748. J Clin Invest. 2002. PMID: 12093886 Free PMC article.
800 results