Tomita T - Search Results

1

Three-dimensional structure of the gamma-secretase complex.

Ogura T, Mio K, Hayashi I, Miyashita H, Fukuda R, Kopan R, Kodama T, Hamakubo T, Iwatsubo T, Tomita T, Sato C. Ogura T, et al. Among authors: tomita t. Biochem Biophys Res Commun. 2006 May 5;343(2):525-34. doi: 10.1016/j.bbrc.2006.02.158. Epub 2006 Mar 9. Biochem Biophys Res Commun. 2006. PMID: 16546128

2

Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4.

Morohashi Y, Hatano N, Ohya S, Takikawa R, Watabiki T, Takasugi N, Imaizumi Y, Tomita T, Iwatsubo T. Morohashi Y, et al. Among authors: tomita t. J Biol Chem. 2002 Apr 26;277(17):14965-75. doi: 10.1074/jbc.M200897200. Epub 2002 Feb 14. J Biol Chem. 2002. PMID: 11847232 Free article.

3

Complex N-glycosylated form of nicastrin is stabilized and selectively bound to presenilin fragments.

Tomita T, Katayama R, Takikawa R, Iwatsubo T. Tomita T, et al. FEBS Lett. 2002 Jun 5;520(1-3):117-21. doi: 10.1016/s0014-5793(02)02802-8. FEBS Lett. 2002. PMID: 12044882 Free article.

4

Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1.

Okochi M, Steiner H, Fukumori A, Tanii H, Tomita T, Tanaka T, Iwatsubo T, Kudo T, Takeda M, Haass C. Okochi M, et al. Among authors: tomita t. EMBO J. 2002 Oct 15;21(20):5408-16. doi: 10.1093/emboj/cdf541. EMBO J. 2002. PMID: 12374741 Free PMC article.

5

The mechanism of gamma-secretase activities through high molecular weight complex formation of presenilins is conserved in Drosophila melanogaster and mammals.

Takasugi N, Takahashi Y, Morohashi Y, Tomita T, Iwatsubo T. Takasugi N, et al. Among authors: tomita t. J Biol Chem. 2002 Dec 20;277(51):50198-205. doi: 10.1074/jbc.M205352200. Epub 2002 Oct 17. J Biol Chem. 2002. PMID: 12388554 Free article.

6

A role for presenilin 1 in regulating the delivery of amyloid precursor protein to the cell surface.

Leem JY, Saura CA, Pietrzik C, Christianson J, Wanamaker C, King LT, Veselits ML, Tomita T, Gasparini L, Iwatsubo T, Xu H, Green WN, Koo EH, Thinakaran G. Leem JY, et al. Among authors: tomita t. Neurobiol Dis. 2002 Oct;11(1):64-82. doi: 10.1006/nbdi.2002.0546. Neurobiol Dis. 2002. PMID: 12460547

7

Presenilin-dependent gamma-secretase activity mediates the intramembranous cleavage of CD44.

Murakami D, Okamoto I, Nagano O, Kawano Y, Tomita T, Iwatsubo T, De Strooper B, Yumoto E, Saya H. Murakami D, et al. Among authors: tomita t. Oncogene. 2003 Mar 13;22(10):1511-6. doi: 10.1038/sj.onc.1206298. Oncogene. 2003. PMID: 12629514

8

Sulindac sulfide is a noncompetitive gamma-secretase inhibitor that preferentially reduces Abeta 42 generation.

Takahashi Y, Hayashi I, Tominari Y, Rikimaru K, Morohashi Y, Kan T, Natsugari H, Fukuyama T, Tomita T, Iwatsubo T. Takahashi Y, et al. Among authors: tomita t. J Biol Chem. 2003 May 16;278(20):18664-70. doi: 10.1074/jbc.M301619200. Epub 2003 Mar 10. J Biol Chem. 2003. PMID: 12637581 Free article.

9

The role of presenilin cofactors in the gamma-secretase complex.

Takasugi N, Tomita T, Hayashi I, Tsuruoka M, Niimura M, Takahashi Y, Thinakaran G, Iwatsubo T. Takasugi N, et al. Among authors: tomita t. Nature. 2003 Mar 27;422(6930):438-41. doi: 10.1038/nature01506. Epub 2003 Mar 16. Nature. 2003. PMID: 12660785

10

A presenilin dimer at the core of the gamma-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis.

Schroeter EH, Ilagan MX, Brunkan AL, Hecimovic S, Li YM, Xu M, Lewis HD, Saxena MT, De Strooper B, Coonrod A, Tomita T, Iwatsubo T, Moore CL, Goate A, Wolfe MS, Shearman M, Kopan R. Schroeter EH, et al. Among authors: tomita t. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):13075-80. doi: 10.1073/pnas.1735338100. Epub 2003 Oct 17. Proc Natl Acad Sci U S A. 2003. PMID: 14566063 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

2,353 results

Search Page

Filters