Manczak M - Search Results

1

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression.

Manczak M, Anekonda TS, Henson E, Park BS, Quinn J, Reddy PH. Manczak M, et al. Hum Mol Genet. 2006 May 1;15(9):1437-49. doi: 10.1093/hmg/ddl066. Epub 2006 Mar 21. Hum Mol Genet. 2006. PMID: 16551656

2

Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage.

Manczak M, Park BS, Jung Y, Reddy PH. Manczak M, et al. Neuromolecular Med. 2004;5(2):147-62. doi: 10.1385/NMM:5:2:147. Neuromolecular Med. 2004. PMID: 15075441

3

Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease.

Reddy PH, McWeeney S, Park BS, Manczak M, Gutala RV, Partovi D, Jung Y, Yau V, Searles R, Mori M, Quinn J. Reddy PH, et al. Among authors: manczak m. Hum Mol Genet. 2004 Jun 15;13(12):1225-40. doi: 10.1093/hmg/ddh140. Epub 2004 Apr 28. Hum Mol Genet. 2004. PMID: 15115763

4

Time-course of mitochondrial gene expressions in mice brains: implications for mitochondrial dysfunction, oxidative damage, and cytochrome c in aging.

Manczak M, Jung Y, Park BS, Partovi D, Reddy PH. Manczak M, et al. J Neurochem. 2005 Feb;92(3):494-504. doi: 10.1111/j.1471-4159.2004.02884.x. J Neurochem. 2005. PMID: 15659220 Free article.

5

Neutralization of granulocyte macrophage colony-stimulating factor decreases amyloid beta 1-42 and suppresses microglial activity in a transgenic mouse model of Alzheimer's disease.

Manczak M, Mao P, Nakamura K, Bebbington C, Park B, Reddy PH. Manczak M, et al. Hum Mol Genet. 2009 Oct 15;18(20):3876-93. doi: 10.1093/hmg/ddp331. Epub 2009 Jul 19. Hum Mol Genet. 2009. PMID: 19617638 Free PMC article.

6

Amyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive decline.

Reddy PH, Manczak M, Mao P, Calkins MJ, Reddy AP, Shirendeb U. Reddy PH, et al. Among authors: manczak m. J Alzheimers Dis. 2010;20 Suppl 2(Suppl 2):S499-512. doi: 10.3233/JAD-2010-100504. J Alzheimers Dis. 2010. PMID: 20413847 Free PMC article. Review.

7

Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons.

Manczak M, Mao P, Calkins MJ, Cornea A, Reddy AP, Murphy MP, Szeto HH, Park B, Reddy PH. Manczak M, et al. J Alzheimers Dis. 2010;20 Suppl 2(Suppl 2):S609-31. doi: 10.3233/JAD-2010-100564. J Alzheimers Dis. 2010. PMID: 20463406 Free PMC article.

8

Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage.

Shirendeb U, Reddy AP, Manczak M, Calkins MJ, Mao P, Tagle DA, Reddy PH. Shirendeb U, et al. Among authors: manczak m. Hum Mol Genet. 2011 Apr 1;20(7):1438-55. doi: 10.1093/hmg/ddr024. Epub 2011 Jan 21. Hum Mol Genet. 2011. PMID: 21257639 Free PMC article.

9

Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.

Manczak M, Calkins MJ, Reddy PH. Manczak M, et al. Hum Mol Genet. 2011 Jul 1;20(13):2495-509. doi: 10.1093/hmg/ddr139. Epub 2011 Mar 31. Hum Mol Genet. 2011. PMID: 21459773 Free PMC article.

10

Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease.

Calkins MJ, Manczak M, Mao P, Shirendeb U, Reddy PH. Calkins MJ, et al. Among authors: manczak m. Hum Mol Genet. 2011 Dec 1;20(23):4515-29. doi: 10.1093/hmg/ddr381. Epub 2011 Aug 25. Hum Mol Genet. 2011. PMID: 21873260 Free PMC article.

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