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The protective effect of the Mycobacterium bovis BCG vaccine is increased by coadministration with the Mycobacterium tuberculosis 72-kilodalton fusion polyprotein Mtb72F in M. tuberculosis-infected guinea pigs.
Brandt L, Skeiky YA, Alderson MR, Lobet Y, Dalemans W, Turner OC, Basaraba RJ, Izzo AA, Lasco TM, Chapman PL, Reed SG, Orme IM. Brandt L, et al. Among authors: dalemans w. Infect Immun. 2004 Nov;72(11):6622-32. doi: 10.1128/IAI.72.11.6622-6632.2004. Infect Immun. 2004. PMID: 15501795 Free PMC article.
Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys.
Reed SG, Coler RN, Dalemans W, Tan EV, DeLa Cruz EC, Basaraba RJ, Orme IM, Skeiky YA, Alderson MR, Cowgill KD, Prieels JP, Abalos RM, Dubois MC, Cohen J, Mettens P, Lobet Y. Reed SG, et al. Among authors: dalemans w. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2301-6. doi: 10.1073/pnas.0712077106. Epub 2009 Feb 2. Proc Natl Acad Sci U S A. 2009. PMID: 19188599 Free PMC article.
Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis.
Williams A, Hatch GJ, Clark SO, Gooch KE, Hatch KA, Hall GA, Huygen K, Ottenhoff TH, Franken KL, Andersen P, Doherty TM, Kaufmann SH, Grode L, Seiler P, Martin C, Gicquel B, Cole ST, Brodin P, Pym AS, Dalemans W, Cohen J, Lobet Y, Goonetilleke N, McShane H, Hill A, Parish T, Smith D, Stoker NG, Lowrie DB, Källenius G, Svenson S, Pawlowski A, Blake K, Marsh PD. Williams A, et al. Among authors: dalemans w. Tuberculosis (Edinb). 2005 Jan-Mar;85(1-2):29-38. doi: 10.1016/j.tube.2004.09.009. Epub 2005 Jan 20. Tuberculosis (Edinb). 2005. PMID: 15687025
Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6.
Langermans JA, Doherty TM, Vervenne RA, van der Laan T, Lyashchenko K, Greenwald R, Agger EM, Aagaard C, Weiler H, van Soolingen D, Dalemans W, Thomas AW, Andersen P. Langermans JA, et al. Among authors: dalemans w. Vaccine. 2005 Apr 15;23(21):2740-50. doi: 10.1016/j.vaccine.2004.11.051. Vaccine. 2005. PMID: 15780721
63 results