Lemaire G - Search Results

1

Identification of new human pregnane X receptor ligands among pesticides using a stable reporter cell system.

Lemaire G, Mnif W, Pascussi JM, Pillon A, Rabenoelina F, Fenet H, Gomez E, Casellas C, Nicolas JC, Cavaillès V, Duchesne MJ, Balaguer P. Lemaire G, et al. Toxicol Sci. 2006 Jun;91(2):501-9. doi: 10.1093/toxsci/kfj173. Epub 2006 Mar 24. Toxicol Sci. 2006. PMID: 16565514

2

Discovery of a highly active ligand of human pregnane x receptor: a case study from pharmacophore modeling and virtual screening to "in vivo" biological activity.

Lemaire G, Benod C, Nahoum V, Pillon A, Boussioux AM, Guichou JF, Subra G, Pascussi JM, Bourguet W, Chavanieu A, Balaguer P. Lemaire G, et al. Mol Pharmacol. 2007 Sep;72(3):572-81. doi: 10.1124/mol.106.033415. Epub 2007 Jun 15. Mol Pharmacol. 2007. PMID: 17573484

3

Activation of retinoic acid receptor-dependent transcription by organochlorine pesticides.

Lemaire G, Balaguer P, Michel S, Rahmani R. Lemaire G, et al. Toxicol Appl Pharmacol. 2005 Jan 1;202(1):38-49. doi: 10.1016/j.taap.2004.06.004. Toxicol Appl Pharmacol. 2005. PMID: 15589975

4

Differential responses of PPARalpha, PPARdelta, and PPARgamma reporter cell lines to selective PPAR synthetic ligands.

Seimandi M, Lemaire G, Pillon A, Perrin A, Carlavan I, Voegel JJ, Vignon F, Nicolas JC, Balaguer P. Seimandi M, et al. Among authors: lemaire g. Anal Biochem. 2005 Sep 1;344(1):8-15. doi: 10.1016/j.ab.2005.06.010. Anal Biochem. 2005. PMID: 16038868

5

Activation of alpha- and beta-estrogen receptors by persistent pesticides in reporter cell lines.

Lemaire G, Mnif W, Mauvais P, Balaguer P, Rahmani R. Lemaire G, et al. Life Sci. 2006 Aug 15;79(12):1160-9. doi: 10.1016/j.lfs.2006.03.023. Epub 2006 Mar 27. Life Sci. 2006. PMID: 16626760

6

A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides.

Lemaire G, de Sousa G, Rahmani R. Lemaire G, et al. Biochem Pharmacol. 2004 Dec 15;68(12):2347-58. doi: 10.1016/j.bcp.2004.07.041. Biochem Pharmacol. 2004. PMID: 15548381

7

Effect of organochlorine pesticides on human androgen receptor activation in vitro.

Lemaire G, Terouanne B, Mauvais P, Michel S, Rahmani R. Lemaire G, et al. Toxicol Appl Pharmacol. 2004 Apr 15;196(2):235-46. doi: 10.1016/j.taap.2003.12.011. Toxicol Appl Pharmacol. 2004. PMID: 15081270

8

Regulation of Bcl-2 and Bcl-xL anti-apoptotic protein expression by nuclear receptor PXR in primary cultures of human and rat hepatocytes.

Zucchini N, de Sousa G, Bailly-Maitre B, Gugenheim J, Bars R, Lemaire G, Rahmani R. Zucchini N, et al. Among authors: lemaire g. Biochim Biophys Acta. 2005 Aug 15;1745(1):48-58. doi: 10.1016/j.bbamcr.2005.02.005. Epub 2005 Mar 18. Biochim Biophys Acta. 2005. PMID: 16085054 Free article.

9

Is CYP1A1 induction always related to AHR signaling pathway?

Delescluse C, Lemaire G, de Sousa G, Rahmani R. Delescluse C, et al. Among authors: lemaire g. Toxicology. 2000 Nov 16;153(1-3):73-82. doi: 10.1016/s0300-483x(00)00305-x. Toxicology. 2000. PMID: 11090948 Review.

10

Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function.

Nahoum V, Pérez E, Germain P, Rodríguez-Barrios F, Manzo F, Kammerer S, Lemaire G, Hirsch O, Royer CA, Gronemeyer H, de Lera AR, Bourguet W. Nahoum V, et al. Among authors: lemaire g. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17323-8. doi: 10.1073/pnas.0705356104. Epub 2007 Oct 18. Proc Natl Acad Sci U S A. 2007. PMID: 17947383 Free PMC article.

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