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Adaptation of the WHO guideline for residual DNA in parenteral vaccines produced on continuous cell lines to a limit for oral vaccines.
Lebron JA, Troilol PJ, Pacchione S, Griffiths TG, Harper LB, Mixson LA, Jackson BE, Michna L, Barnum AB, Denisova L, Johnson CN, Maurer KL, Morgan-Hoffman S, Niu Z, Roden DF, Wang Z, Wolf JJ, Hamilton TR, Laux KM, Soper KA, Ledwith BJ. Lebron JA, et al. Among authors: barnum ab. Dev Biol (Basel). 2006;123:35-44; discussion 55-73. Dev Biol (Basel). 2006. PMID: 16566435
Plasmid DNA vaccines: assay for integration into host genomic DNA.
Ledwith BJ, Manam S, Troilo PJ, Barnum AB, Pauley CJ, Griffiths TG 2nd, Harper LB, Schock HB, Zhang H, Faris JE, Way PA, Beare CM, Bagdon WJ, Nichols WW. Ledwith BJ, et al. Among authors: barnum ab. Dev Biol (Basel). 2000;104:33-43. Dev Biol (Basel). 2000. PMID: 11713822
Tumorigenicity assessments of Per.C6 cells and of an Ad5-vectored HIV-1 vaccine produced on this continuous cell line.
Ledwith BJ, Lanning CL, Gumprecht LA, Anderson CA, Coleman JB, Gatto NT, Balasubramanian G, Farris GM, Kemp RK, Harper LB, Barnum AB, Pacchione SJ, Mauer KL, Troilo PF, Brown ER, Wolf JJ, Lebronl JA, Lewis JA, Nichols WW. Ledwith BJ, et al. Among authors: barnum ab. Dev Biol (Basel). 2006;123:251-63; discussion 265-6. Dev Biol (Basel). 2006. PMID: 16566451