Therrien M - Search Results

1

A KSR/CNK complex mediated by HYP, a novel SAM domain-containing protein, regulates RAS-dependent RAF activation in Drosophila.

Douziech M, Sahmi M, Laberge G, Therrien M. Douziech M, et al. Among authors: therrien m. Genes Dev. 2006 Apr 1;20(7):807-19. doi: 10.1101/gad.1390406. Genes Dev. 2006. PMID: 16600912 Free PMC article.

2

Protein phosphatase 2A positively and negatively regulates Ras1-mediated photoreceptor development in Drosophila.

Wassarman DA, Solomon NM, Chang HC, Karim FD, Therrien M, Rubin GM. Wassarman DA, et al. Among authors: therrien m. Genes Dev. 1996 Feb 1;10(3):272-8. doi: 10.1101/gad.10.3.272. Genes Dev. 1996. PMID: 8595878 Free article.

3

KSR modulates signal propagation within the MAPK cascade.

Therrien M, Michaud NR, Rubin GM, Morrison DK. Therrien M, et al. Genes Dev. 1996 Nov 1;10(21):2684-95. doi: 10.1101/gad.10.21.2684. Genes Dev. 1996. PMID: 8946910 Free article.

4

KSR is a scaffold required for activation of the ERK/MAPK module.

Roy F, Laberge G, Douziech M, Ferland-McCollough D, Therrien M. Roy F, et al. Among authors: therrien m. Genes Dev. 2002 Feb 15;16(4):427-38. doi: 10.1101/gad.962902. Genes Dev. 2002. PMID: 11850406 Free PMC article.

5

MAP kinase module: the Ksr connection.

Roy F, Therrien M. Roy F, et al. Among authors: therrien m. Curr Biol. 2002 Apr 30;12(9):R325-7. doi: 10.1016/s0960-9822(02)00831-x. Curr Biol. 2002. PMID: 12007434 Free article.

6

Bimodal regulation of RAF by CNK in Drosophila.

Douziech M, Roy F, Laberge G, Lefrançois M, Armengod AV, Therrien M. Douziech M, et al. Among authors: therrien m. EMBO J. 2003 Oct 1;22(19):5068-78. doi: 10.1093/emboj/cdg506. EMBO J. 2003. PMID: 14517245 Free PMC article.

7

Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism.

Laberge G, Douziech M, Therrien M. Laberge G, et al. Among authors: therrien m. EMBO J. 2005 Feb 9;24(3):487-98. doi: 10.1038/sj.emboj.7600558. Epub 2005 Jan 20. EMBO J. 2005. PMID: 15660123 Free PMC article.

8

Alphabet, a Ser/Thr phosphatase of the protein phosphatase 2C family, negatively regulates RAS/MAPK signaling in Drosophila.

Baril C, Therrien M. Baril C, et al. Among authors: therrien m. Dev Biol. 2006 Jun 1;294(1):232-45. doi: 10.1016/j.ydbio.2006.02.046. Epub 2006 Apr 4. Dev Biol. 2006. PMID: 16600208 Free article.

9

KSR and CNK: two scaffolds regulating RAS-mediated RAF activation.

Clapéron A, Therrien M. Clapéron A, et al. Among authors: therrien m. Oncogene. 2007 May 14;26(22):3143-58. doi: 10.1038/sj.onc.1210408. Oncogene. 2007. PMID: 17496912 Review.

10

CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.

Rajakulendran T, Sahmi M, Kurinov I, Tyers M, Therrien M, Sicheri F. Rajakulendran T, et al. Among authors: therrien m. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2836-41. doi: 10.1073/pnas.0709705105. Epub 2008 Feb 19. Proc Natl Acad Sci U S A. 2008. PMID: 18287031 Free PMC article.

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