Eichler J - Search Results

1

Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells.

Stuhlmann-Laeisz C, Lang S, Chalaris A, Krzysztof P, Enge S, Eichler J, Klingmüller U, Samuel M, Ernst M, Rose-John S, Scheller J. Stuhlmann-Laeisz C, et al. Among authors: eichler j. Mol Biol Cell. 2006 Jul;17(7):2986-95. doi: 10.1091/mbc.e05-12-1129. Epub 2006 Apr 19. Mol Biol Cell. 2006. PMID: 16624864 Free PMC article.

2

Development of a monoclonal antibody-based enzyme-linked immunoabsorbent assay for the binding of gp130 to the IL-6/IL-6R complex and its competitive inhibition.

Scheller J, Kovaleva M, Rabe B, Eichler J, Kallen KJ, Rose-John S. Scheller J, et al. Among authors: eichler j. J Immunol Methods. 2004 Aug;291(1-2):93-100. doi: 10.1016/j.jim.2004.05.002. J Immunol Methods. 2004. PMID: 15345308

3

Abrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage display.

Kovaleva M, Bussmeyer I, Rabe B, Grötzinger J, Sudarman E, Eichler J, Conrad U, Rose-John S, Scheller J. Kovaleva M, et al. Among authors: eichler j. J Virol. 2006 Sep;80(17):8510-20. doi: 10.1128/JVI.00420-06. J Virol. 2006. PMID: 16912301 Free PMC article.

4

Synthetic mimetics of the gp130 binding site for viral interleukin-6 as inhibitors of the vIL-6-gp130 interaction.

Sudarman E, Bollati-Fogolín M, Hafner M, Müller W, Scheller J, Rose-John S, Eichler J. Sudarman E, et al. Among authors: eichler j. Chem Biol Drug Des. 2008 May;71(5):494-500. doi: 10.1111/j.1747-0285.2008.00649.x. Epub 2008 Mar 25. Chem Biol Drug Des. 2008. PMID: 18373551

5

Computational Characterization of the Binding Properties of the HIV1-Neutralizing Antibody PG16 and Design of PG16-Derived CDRH3 Peptides.

Deubler M, Weißenborn L, Leukel S, Horn AHC, Eichler J, Sticht H. Deubler M, et al. Among authors: eichler j. Biology (Basel). 2023 Jun 6;12(6):824. doi: 10.3390/biology12060824. Biology (Basel). 2023. PMID: 37372110 Free PMC article.

6

Structure-based synthetic mimicry of discontinuous protein binding sites: inhibitors of the interaction of Mena EVH1 domain with proline-rich ligands.

Hunke C, Hirsch T, Eichler J. Hunke C, et al. Among authors: eichler j. Chembiochem. 2006 Aug;7(8):1258-64. doi: 10.1002/cbic.200500465. Chembiochem. 2006. PMID: 16810654 Free article.

7

A rationally designed synthetic mimic of the discontinuous CD4-binding site of HIV-1 gp120.

Franke R, Hirsch T, Eichler J. Franke R, et al. Among authors: eichler j. J Recept Signal Transduct Res. 2006;26(5-6):453-60. doi: 10.1080/10799890600923179. J Recept Signal Transduct Res. 2006. PMID: 17118792

8

Synthetic mimetics of the CD4 binding site of HIV-1 gp120 for the design of immunogens.

Franke R, Hirsch T, Overwin H, Eichler J. Franke R, et al. Among authors: eichler j. Angew Chem Int Ed Engl. 2007;46(8):1253-5. doi: 10.1002/anie.200603274. Angew Chem Int Ed Engl. 2007. PMID: 17211914 Free article. No abstract available.

9

Peptides as protein binding site mimetics.

Eichler J. Eichler J. Curr Opin Chem Biol. 2008 Dec;12(6):707-13. doi: 10.1016/j.cbpa.2008.09.023. Epub 2008 Oct 18. Curr Opin Chem Biol. 2008. PMID: 18935974 Review.

10

Solid-phase synthesis of structurally diverse scaffolded peptides for the mimicry of discontinuous protein binding sites.

Franke R, Doll C, Wray V, Eichler J. Franke R, et al. Among authors: eichler j. Protein Pept Lett. 2003 Dec;10(6):531-9. doi: 10.2174/0929866033478519. Protein Pept Lett. 2003. PMID: 14683504

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