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Page 1
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses.
Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, Matsui K, Uematsu S, Jung A, Kawai T, Ishii KJ, Yamaguchi O, Otsu K, Tsujimura T, Koh CS, Reis e Sousa C, Matsuura Y, Fujita T, Akira S. Kato H, et al. Among authors: otsu k. Nature. 2006 May 4;441(7089):101-5. doi: 10.1038/nature04734. Epub 2006 Apr 9. Nature. 2006. PMID: 16625202
The small GTP-binding protein Rac1 induces cardiac myocyte hypertrophy through the activation of apoptosis signal-regulating kinase 1 and nuclear factor-kappa B.
Higuchi Y, Otsu K, Nishida K, Hirotani S, Nakayama H, Yamaguchi O, Hikoso S, Kashiwase K, Takeda T, Watanabe T, Mano T, Matsumura Y, Ueno H, Hori M. Higuchi Y, et al. Among authors: otsu k. J Biol Chem. 2003 Jun 6;278(23):20770-7. doi: 10.1074/jbc.M213203200. Epub 2003 Apr 2. J Biol Chem. 2003. PMID: 12672819 Free article.
Ca(2+)-sensitive tyrosine kinase Pyk2/CAK beta-dependent signaling is essential for G-protein-coupled receptor agonist-induced hypertrophy.
Hirotani S, Higuchi Y, Nishida K, Nakayama H, Yamaguchi O, Hikoso S, Takeda T, Kashiwase K, Watanabe T, Asahi M, Taniike M, Tsujimoto I, Matsumura Y, Sasaki T, Hori M, Otsu K. Hirotani S, et al. Among authors: otsu k. J Mol Cell Cardiol. 2004 Jun;36(6):799-807. doi: 10.1016/j.yjmcc.2004.03.002. J Mol Cell Cardiol. 2004. PMID: 15158121
Cardiac-specific overexpression of sarcolipin inhibits sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA2a) activity and impairs cardiac function in mice.
Asahi M, Otsu K, Nakayama H, Hikoso S, Takeda T, Gramolini AO, Trivieri MG, Oudit GY, Morita T, Kusakari Y, Hirano S, Hongo K, Hirotani S, Yamaguchi O, Peterson A, Backx PH, Kurihara S, Hori M, MacLennan DH. Asahi M, et al. Among authors: otsu k. Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9199-204. doi: 10.1073/pnas.0402596101. Epub 2004 Jun 16. Proc Natl Acad Sci U S A. 2004. PMID: 15201433 Free PMC article.
Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis.
Yamaguchi O, Watanabe T, Nishida K, Kashiwase K, Higuchi Y, Takeda T, Hikoso S, Hirotani S, Asahi M, Taniike M, Nakai A, Tsujimoto I, Matsumura Y, Miyazaki J, Chien KR, Matsuzawa A, Sadamitsu C, Ichijo H, Baccarini M, Hori M, Otsu K. Yamaguchi O, et al. Among authors: otsu k. J Clin Invest. 2004 Oct;114(7):937-43. doi: 10.1172/JCI20317. J Clin Invest. 2004. PMID: 15467832 Free PMC article.
333 results