Ryan TM - Search Results

1

Correction of sickle cell disease by homologous recombination in embryonic stem cells.

Wu LC, Sun CW, Ryan TM, Pawlik KM, Ren J, Townes TM. Wu LC, et al. Among authors: ryan tm. Blood. 2006 Aug 15;108(4):1183-8. doi: 10.1182/blood-2006-02-004812. Epub 2006 Apr 25. Blood. 2006. PMID: 16638928 Free PMC article.

2

Correction of a mouse model of sickle cell disease: lentiviral/antisickling beta-globin gene transduction of unmobilized, purified hematopoietic stem cells.

Levasseur DN, Ryan TM, Pawlik KM, Townes TM. Levasseur DN, et al. Among authors: ryan tm. Blood. 2003 Dec 15;102(13):4312-9. doi: 10.1182/blood-2003-04-1251. Epub 2003 Aug 21. Blood. 2003. PMID: 12933581 Free article.

3

Rapid tagging of endogenous mouse genes by recombineering and ES cell complementation of tetraploid blastocysts.

Zhou D, Ren JX, Ryan TM, Higgins NP, Townes TM. Zhou D, et al. Among authors: ryan tm. Nucleic Acids Res. 2004 Sep 8;32(16):e128. doi: 10.1093/nar/gnh128. Nucleic Acids Res. 2004. PMID: 15356288 Free PMC article.

4

Mouse model of human beta zero thalassemia: targeted deletion of the mouse beta maj- and beta min-globin genes in embryonic stem cells.

Ciavatta DJ, Ryan TM, Farmer SC, Townes TM. Ciavatta DJ, et al. Among authors: ryan tm. Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9259-63. doi: 10.1073/pnas.92.20.9259. Proc Natl Acad Sci U S A. 1995. PMID: 7568113 Free PMC article.

5

Knockout-transgenic mouse model of sickle cell disease.

Ryan TM, Ciavatta DJ, Townes TM. Ryan TM, et al. Science. 1997 Oct 31;278(5339):873-6. doi: 10.1126/science.278.5339.873. Science. 1997. PMID: 9346487

6

Distinguishable live erythroid and myeloid cells in beta-globin ECFP x lysozyme EGFP mice.

Heck S, Ermakova O, Iwasaki H, Akashi K, Sun CW, Ryan TM, Townes T, Graf T. Heck S, et al. Among authors: ryan tm. Blood. 2003 Feb 1;101(3):903-6. doi: 10.1182/blood-2002-06-1861. Epub 2002 Sep 26. Blood. 2003. PMID: 12393544 Free article.

7

A recombinant human hemoglobin with anti-sickling properties greater than fetal hemoglobin.

Levasseur DN, Ryan TM, Reilly MP, McCune SL, Asakura T, Townes TM. Levasseur DN, et al. Among authors: ryan tm. J Biol Chem. 2004 Jun 25;279(26):27518-24. doi: 10.1074/jbc.M402578200. Epub 2004 Apr 14. J Biol Chem. 2004. PMID: 15084588 Free article.

8

Humanized Mouse Model of Cooley's Anemia.

Huo Y, McConnell SC, Liu SR, Yang R, Zhang TT, Sun CW, Wu LC, Ryan TM. Huo Y, et al. Among authors: ryan tm. J Biol Chem. 2009 Feb 20;284(8):4889-96. doi: 10.1074/jbc.M805681200. Epub 2008 Dec 19. J Biol Chem. 2009. PMID: 19098001 Free PMC article.

9

Humanized mouse models of Cooley's anemia: correct fetal-to-adult hemoglobin switching, disease onset, and disease pathology.

Huo Y, McConnell SC, Liu S, Zhang T, Yang R, Ren J, Ryan TM. Huo Y, et al. Among authors: ryan tm. Ann N Y Acad Sci. 2010 Aug;1202:45-51. doi: 10.1111/j.1749-6632.2010.05547.x. Ann N Y Acad Sci. 2010. PMID: 20712771 Free PMC article.

10

Nitric oxide-dependent generation of reactive species in sickle cell disease. Actin tyrosine induces defective cytoskeletal polymerization.

Aslan M, Ryan TM, Townes TM, Coward L, Kirk MC, Barnes S, Alexander CB, Rosenfeld SS, Freeman BA. Aslan M, et al. Among authors: ryan tm. J Biol Chem. 2003 Feb 7;278(6):4194-204. doi: 10.1074/jbc.M208916200. Epub 2002 Oct 24. J Biol Chem. 2003. PMID: 12401783 Free article.

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