Nevalainen T - Search Results

1

Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide.

Parkkari T, Savinainen JR, Raitio KH, Saario SM, Matilainen L, Sirviö T, Laitinen JT, Nevalainen T, Niemi R, Järvinen T. Parkkari T, et al. Among authors: nevalainen t. Bioorg Med Chem. 2006 Aug 1;14(15):5252-8. doi: 10.1016/j.bmc.2006.03.051. Epub 2006 Apr 27. Bioorg Med Chem. 2006. PMID: 16644227

2

Piperazine and piperidine carboxamides and carbamates as inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL).

Korhonen J, Kuusisto A, van Bruchem J, Patel JZ, Laitinen T, Navia-Paldanius D, Laitinen JT, Savinainen JR, Parkkari T, Nevalainen TJ. Korhonen J, et al. Among authors: nevalainen tj. Bioorg Med Chem. 2014 Dec 1;22(23):6694-6705. doi: 10.1016/j.bmc.2014.09.012. Epub 2014 Sep 16. Bioorg Med Chem. 2014. PMID: 25282655

3

Loratadine analogues as MAGL inhibitors.

Patel JZ, Ahenkorah S, Vaara M, Staszewski M, Adams Y, Laitinen T, Navia-Paldanius D, Parkkari T, Savinainen JR, Walczyński K, Laitinen JT, Nevalainen TJ. Patel JZ, et al. Among authors: nevalainen tj. Bioorg Med Chem Lett. 2015 Apr 1;25(7):1436-42. doi: 10.1016/j.bmcl.2015.02.037. Epub 2015 Feb 24. Bioorg Med Chem Lett. 2015. PMID: 25752982

4

Revisiting 1,3,4-Oxadiazol-2-ones: Utilization in the Development of ABHD6 Inhibitors.

Patel JZ, van Bruchem J, Laitinen T, Kaczor AA, Navia-Paldanius D, Parkkari T, Savinainen JR, Laitinen JT, Nevalainen TJ. Patel JZ, et al. Among authors: nevalainen tj. Bioorg Med Chem. 2015 Oct 1;23(19):6335-45. doi: 10.1016/j.bmc.2015.08.030. Epub 2015 Aug 28. Bioorg Med Chem. 2015. PMID: 26344596

5

Potent and selective N-(4-sulfamoylphenyl)thiourea-based GPR55 agonists.

Yrjölä S, Parkkari T, Navia-Paldanius D, Laitinen T, Kaczor AA, Kokkola T, Adusei-Mensah F, Savinainen JR, Laitinen JT, Poso A, Alexander A, Penman J, Stott L, Anskat M, Irving AJ, Nevalainen TJ. Yrjölä S, et al. Among authors: nevalainen tj. Eur J Med Chem. 2016 Jan 1;107:119-32. doi: 10.1016/j.ejmech.2015.10.050. Epub 2015 Nov 2. Eur J Med Chem. 2016. PMID: 26575458

6

Synthesis and CB1 receptor activities of novel arachidonyl alcohol derivatives.

Parkkari T, Savinainen JR, Rauhala AL, Tolonen TL, Nevalainen T, Laitinen JT, Gynther J, Järvinen T. Parkkari T, et al. Among authors: nevalainen t. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3231-4. doi: 10.1016/j.bmcl.2004.03.093. Bioorg Med Chem Lett. 2004. PMID: 15149681

7

Characterization of the sulfhydryl-sensitive site in the enzyme responsible for hydrolysis of 2-arachidonoyl-glycerol in rat cerebellar membranes.

Saario SM, Salo OM, Nevalainen T, Poso A, Laitinen JT, Järvinen T, Niemi R. Saario SM, et al. Among authors: nevalainen t. Chem Biol. 2005 Jun;12(6):649-56. doi: 10.1016/j.chembiol.2005.04.013. Chem Biol. 2005. PMID: 15975510

8

Virtual screening of novel CB2 ligands using a comparative model of the human cannabinoid CB2 receptor.

Salo OM, Raitio KH, Savinainen JR, Nevalainen T, Lahtela-Kakkonen M, Laitinen JT, Järvinen T, Poso A. Salo OM, et al. Among authors: nevalainen t. J Med Chem. 2005 Nov 17;48(23):7166-71. doi: 10.1021/jm050565b. J Med Chem. 2005. PMID: 16279774

9

Synthesis and CB1 receptor activities of dimethylheptyl derivatives of 2-arachidonoyl glycerol (2-AG) and 2-arachidonyl glyceryl ether (2-AGE).

Parkkari T, Salo OM, Huttunen KM, Savinainen JR, Laitinen JT, Poso A, Nevalainen T, Järvinen T. Parkkari T, et al. Among authors: nevalainen t. Bioorg Med Chem. 2006 Apr 15;14(8):2850-8. doi: 10.1016/j.bmc.2005.12.007. Epub 2006 Jan 5. Bioorg Med Chem. 2006. PMID: 16403642

10

3D-QSAR studies on cannabinoid CB1 receptor agonists: G-protein activation as biological data.

Salo OM, Savinainen JR, Parkkari T, Nevalainen T, Lahtela-Kakkonen M, Gynther J, Laitinen JT, Järvinen T, Poso A. Salo OM, et al. Among authors: nevalainen t. J Med Chem. 2006 Jan 26;49(2):554-66. doi: 10.1021/jm0505157. J Med Chem. 2006. PMID: 16420041

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