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Minerval (2-hydroxyoleic acid) causes cancer cell selective toxicity by uncoupling oxidative phosphorylation and compromising bioenergetic compensation capacity.
Massalha W, Markovits M, Pichinuk E, Feinstein-Rotkopf Y, Tarshish M, Mishra K, Llado V, Weil M, Escriba PV, Kakhlon O. Massalha W, et al. Among authors: tarshish m. Biosci Rep. 2019 Jan 18;39(1):BSR20181661. doi: 10.1042/BSR20181661. Print 2019 Jan 31. Biosci Rep. 2019. PMID: 30602451 Free PMC article.
Dual-Targeted Autoimmune Sword in Fatal Epilepsy: Patient's glutamate receptor AMPA GluR3B peptide autoimmune antibodies bind, induce Reactive Oxygen Species (ROS) in, and kill both human neural cells and T cells.
Levite M, Zelig D, Friedman A, Ilouz N, Eilam R, Bromberg Z, Ramadhan Lasu AA, Arbel-Alon S, Edvardson S, Tarshish M, Riek LP, Lako RL, Reubinoff B, Lebendiker M, Yaish D, Stavsky A, Galun E. Levite M, et al. Among authors: tarshish m. J Autoimmun. 2020 Aug;112:102462. doi: 10.1016/j.jaut.2020.102462. Epub 2020 Apr 10. J Autoimmun. 2020. PMID: 32561150