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Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to switch off Nrf2-mediated antioxidant activation of cytoprotective gene expression.
Niture SK, Jain AK, Shelton PM, Jaiswal AK. Niture SK, et al. Among authors: jain ak. J Biol Chem. 2011 Aug 19;286(33):28821-28834. doi: 10.1074/jbc.M111.255042. Epub 2011 Jun 20. J Biol Chem. 2011. Retraction in: J Biol Chem. 2017 Feb 3;292(5):2048. doi: 10.1074/jbc.A117.255042. PMID: 21690096 Free PMC article. Retracted.
Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance.
Niture SK, Jain AK, Jaiswal AK. Niture SK, et al. Among authors: jain ak. J Cell Sci. 2009 Dec 15;122(Pt 24):4452-64. doi: 10.1242/jcs.058537. Epub 2009 Nov 17. J Cell Sci. 2009. Retraction in: J Cell Sci. 2017 Feb 15;130(4):816. doi: 10.1242/jcs.202093. PMID: 19920073 Free PMC article. Retracted.
1,423 results