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Pleiotrophin is highly expressed by myeloma cells and promotes myeloma tumor growth.
Chen H, Gordon MS, Campbell RA, Li M, Wang CS, Lee HJ, Sanchez E, Manyak SJ, Gui D, Shalitin D, Said J, Chang Y, Deuel TF, Baritaki S, Bonavida B, Berenson JR. Chen H, et al. Blood. 2007 Jul 1;110(1):287-95. doi: 10.1182/blood-2006-08-042374. Epub 2007 Mar 16. Blood. 2007. PMID: 17369488 Free article.
Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis.
Chen H, Campbell RA, Chang Y, Li M, Wang CS, Li J, Sanchez E, Share M, Steinberg J, Berenson A, Shalitin D, Zeng Z, Gui D, Perez-Pinera P, Berenson RJ, Said J, Bonavida B, Deuel TF, Berenson JR. Chen H, et al. Blood. 2009 Feb 26;113(9):1992-2002. doi: 10.1182/blood-2008-02-133751. Epub 2008 Dec 5. Blood. 2009. PMID: 19060246 Free PMC article.
Serum B-cell maturation antigen is elevated in multiple myeloma and correlates with disease status and survival.
Sanchez E, Li M, Kitto A, Li J, Wang CS, Kirk DT, Yellin O, Nichols CM, Dreyer MP, Ahles CP, Robinson A, Madden E, Waterman GN, Swift RA, Bonavida B, Boccia R, Vescio RA, Crowley J, Chen H, Berenson JR. Sanchez E, et al. Br J Haematol. 2012 Sep;158(6):727-38. doi: 10.1111/j.1365-2141.2012.09241.x. Epub 2012 Jul 18. Br J Haematol. 2012. PMID: 22804669 Free article.
Serum B-cell maturation antigen: a novel biomarker to predict outcomes for multiple myeloma patients.
Ghermezi M, Li M, Vardanyan S, Harutyunyan NM, Gottlieb J, Berenson A, Spektor TM, Andreu-Vieyra C, Petraki S, Sanchez E, Udd K, Wang CS, Swift RA, Chen H, Berenson JR. Ghermezi M, et al. Among authors: wang cs. Haematologica. 2017 Apr;102(4):785-795. doi: 10.3324/haematol.2016.150896. Epub 2016 Dec 29. Haematologica. 2017. PMID: 28034989 Free PMC article.
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