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Quadruple-2 protease inhibitors (PI)-therapy does not accelerate viral decay and suppression in PI-naive HIV-1 infected patients with severe immunosuppression and high viral load as compared with standard triple therapy.
Portilla J, Boix V, Garcia-Henarejos JA, Llopis C, Martínez-Madrid O, Gimeno A, Sánchez-Paya J, Merino E. Portilla J, et al. Int J STD AIDS. 2005 Dec;16(12):807-10. doi: 10.1258/095646205774988082. Int J STD AIDS. 2005. PMID: 16336763 Clinical Trial.
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