Wu WL - Search Results

1

Synthesis and structure-activity relationships of piperidine-based melanin-concentrating hormone receptor 1 antagonists.

Wu WL, Burnett DA, Spring R, Qiang L, Sasikumar TK, Domalski MS, Greenlee WJ, O'Neill K, Hawes BE. Wu WL, et al. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3668-73. doi: 10.1016/j.bmcl.2006.04.061. Epub 2006 May 11. Bioorg Med Chem Lett. 2006. PMID: 16690312

2

Synthesis and structure-activity relationships of aminoalkylazetidines as ORL1 receptor ligands.

Wu WL, Caplen MA, Domalski MS, Zhang H, Fawzi A, Burnett DA. Wu WL, et al. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3157-60. doi: 10.1016/s0960-894x(02)00652-2. Bioorg Med Chem Lett. 2002. PMID: 12372523

3

Dopamine D1/D5 receptor antagonists with improved pharmacokinetics: design, synthesis, and biological evaluation of phenol bioisosteric analogues of benzazepine D1/D5 antagonists.

Wu WL, Burnett DA, Spring R, Greenlee WJ, Smith M, Favreau L, Fawzi A, Zhang H, Lachowicz JE. Wu WL, et al. J Med Chem. 2005 Feb 10;48(3):680-93. doi: 10.1021/jm030614p. J Med Chem. 2005. PMID: 15689153

4

Design and synthesis of orally efficacious benzimidazoles as melanin-concentrating hormone receptor 1 antagonists.

Wu WL, Burnett DA, Caplen MA, Domalski MS, Bennett C, Greenlee WJ, Hawes BE, O'Neill K, Weig B, Weston D, Spar B, Kowalski T. Wu WL, et al. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3674-8. doi: 10.1016/j.bmcl.2006.04.062. Epub 2006 May 11. Bioorg Med Chem Lett. 2006. PMID: 16690315

5

Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic pain.

Wu WL, Burnett DA, Domalski M, Greenlee WJ, Li C, Bertorelli R, Fredduzzi S, Lozza G, Veltri A, Reggiani A. Wu WL, et al. J Med Chem. 2007 Nov 15;50(23):5550-3. doi: 10.1021/jm070590c. Epub 2007 Oct 11. J Med Chem. 2007. PMID: 17929793

6

Design and synthesis of tricyclic sulfones as gamma-secretase inhibitors with greatly reduced Notch toxicity.

Xu R, Cole D, Asberom T, Bara T, Bennett C, Burnett DA, Clader J, Domalski M, Greenlee W, Hyde L, Josien H, Li H, McBriar M, McKittrick B, McPhail AT, Pissarnitski D, Qiang L, Rajagopalan M, Sasikumar T, Su J, Tang H, Wu WL, Zhang L, Zhao Z. Xu R, et al. Among authors: wu wl. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2591-6. doi: 10.1016/j.bmcl.2010.02.080. Epub 2010 Feb 23. Bioorg Med Chem Lett. 2010. PMID: 20236824

7

Tetracyclic sulfones as potent gamma-secretase inhibitors: synthesis and structure-activity relationship studies.

Sasikumar TK, Burnett DA, Asberom T, Wu WL, Bennett C, Cole D, Xu R, Greenlee WJ, Clader J, Zhang L, Hyde L. Sasikumar TK, et al. Among authors: wu wl. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3645-8. doi: 10.1016/j.bmcl.2010.04.103. Epub 2010 Apr 28. Bioorg Med Chem Lett. 2010. PMID: 20471254

8

Fused tricyclic mGluR1 antagonists for the treatment of neuropathic pain.

Bennett CE, Burnett DA, Greenlee WJ, Knutson CE, Korakas P, Li C, Tulshian D, Wu WL, Bertorelli R, Fredduzzi S, Grilli M, Lozza G, Reggiani A, Veltri A. Bennett CE, et al. Among authors: wu wl. Bioorg Med Chem Lett. 2012 Feb 15;22(4):1575-8. doi: 10.1016/j.bmcl.2011.12.131. Epub 2012 Jan 3. Bioorg Med Chem Lett. 2012. PMID: 22266036

9

Synthesis and SAR development of novel mGluR1 antagonists for the treatment of chronic pain.

Brumfield S, Korakas P, Silverman LS, Tulshian D, Matasi JJ, Qiang L, Bennett CE, Burnett DA, Greenlee WJ, Knutson CE, Wu WL, Sasikumar TK, Domalski M, Bertorelli R, Grilli M, Lozza G, Reggiani A, Li C. Brumfield S, et al. Among authors: wu wl. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7223-6. doi: 10.1016/j.bmcl.2012.09.048. Epub 2012 Oct 2. Bioorg Med Chem Lett. 2012. PMID: 23084894

10

Structure activity relationship studies of tricyclic bispyran sulfone γ-secretase inhibitors.

Wu WL, Asberom T, Bara T, Bennett C, Burnett DA, Clader J, Domalski M, Greenlee WJ, Josien H, McBriar M, Rajagopalan M, Vicarel M, Xu R, Hyde LA, Del Vecchio RA, Cohen-Williams ME, Song L, Lee J, Terracina G, Zhang Q, Nomeir A, Parker EM, Zhang L. Wu WL, et al. Bioorg Med Chem Lett. 2013 Feb 1;23(3):844-9. doi: 10.1016/j.bmcl.2012.11.047. Epub 2012 Nov 24. Bioorg Med Chem Lett. 2013. PMID: 23265892

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

531 results

Search Page

Filters