Yoshida S - Search Results

1

Antagonism of peroxisome proliferator-activated receptor gamma prevents high-fat diet-induced obesity in vivo.

Nakano R, Kurosaki E, Yoshida S, Yokono M, Shimaya A, Maruyama T, Shibasaki M. Nakano R, et al. Among authors: yoshida s. Biochem Pharmacol. 2006 Jun 28;72(1):42-52. doi: 10.1016/j.bcp.2006.03.023. Epub 2006 Apr 7. Biochem Pharmacol. 2006. PMID: 16696951

2

Differential effects of YM440 a hypoglycemic agent on binding to a peroxisome proliferator-activated receptor gamma and its transactivation.

Kurosaki E, Nakano R, Shimaya A, Yoshida S, Ida M, Suzuki T, Shibasaki M, Shikama H. Kurosaki E, et al. Among authors: yoshida s. Biochem Pharmacol. 2003 Mar 1;65(5):795-805. doi: 10.1016/s0006-2952(02)01617-9. Biochem Pharmacol. 2003. PMID: 12628477

3

Identification of a novel GPR119 agonist, AS1269574, with in vitro and in vivo glucose-stimulated insulin secretion.

Yoshida S, Ohishi T, Matsui T, Shibasaki M. Yoshida S, et al. Biochem Biophys Res Commun. 2010 Sep 24;400(3):437-41. doi: 10.1016/j.bbrc.2010.08.097. Epub 2010 Sep 16. Biochem Biophys Res Commun. 2010. PMID: 20804735

4

Novel GPR119 agonist AS1535907 contributes to first-phase insulin secretion in rat perfused pancreas and diabetic db/db mice.

Yoshida S, Ohishi T, Matsui T, Tanaka H, Oshima H, Yonetoku Y, Shibasaki M. Yoshida S, et al. Biochem Biophys Res Commun. 2010 Nov 12;402(2):280-5. doi: 10.1016/j.bbrc.2010.10.015. Epub 2010 Oct 16. Biochem Biophys Res Commun. 2010. PMID: 20937249

5

Chronic treatment with novel GPR40 agonists improve whole-body glucose metabolism based on the glucose-dependent insulin secretion.

Tanaka H, Yoshida S, Oshima H, Minoura H, Negoro K, Yamazaki T, Sakuda S, Iwasaki F, Matsui T, Shibasaki M. Tanaka H, et al. Among authors: yoshida s. J Pharmacol Exp Ther. 2013 Sep;346(3):443-52. doi: 10.1124/jpet.113.206466. Epub 2013 Jul 12. J Pharmacol Exp Ther. 2013. PMID: 23853170 Free article.

6

Novel GPR40 agonist AS2575959 exhibits glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion.

Tanaka H, Yoshida S, Minoura H, Negoro K, Shimaya A, Shimokawa T, Shibasaki M. Tanaka H, et al. Among authors: yoshida s. Life Sci. 2014 Jan 17;94(2):115-21. doi: 10.1016/j.lfs.2013.11.010. Epub 2013 Nov 21. Life Sci. 2014. PMID: 24269216

7

AS1907417, a novel GPR119 agonist, as an insulinotropic and β-cell preservative agent for the treatment of type 2 diabetes.

Yoshida S, Tanaka H, Oshima H, Yamazaki T, Yonetoku Y, Ohishi T, Matsui T, Shibasaki M. Yoshida S, et al. Biochem Biophys Res Commun. 2010 Oct 1;400(4):745-51. doi: 10.1016/j.bbrc.2010.08.141. Epub 2010 Sep 15. Biochem Biophys Res Commun. 2010. PMID: 20816753

8

Novel GPR119 agonist AS1669058 potentiates insulin secretion from rat islets and has potent anti-diabetic effects in ICR and diabetic db/db mice.

Oshima H, Yoshida S, Ohishi T, Matsui T, Tanaka H, Yonetoku Y, Shibasaki M, Uchiyama Y. Oshima H, et al. Among authors: yoshida s. Life Sci. 2013 Feb 7;92(2):167-73. doi: 10.1016/j.lfs.2012.11.015. Epub 2012 Dec 13. Life Sci. 2013. PMID: 23246743

9

The role of small molecule GPR119 agonist, AS1535907, in glucose-stimulated insulin secretion and pancreatic β-cell function.

Yoshida S, Ohishi T, Matsui T, Tanaka H, Oshima H, Yonetoku Y, Shibasaki M. Yoshida S, et al. Diabetes Obes Metab. 2011 Jan;13(1):34-41. doi: 10.1111/j.1463-1326.2010.01315.x. Diabetes Obes Metab. 2011. PMID: 21114601

10

Discovery and biological evaluation of novel 4-amino-2-phenylpyrimidine derivatives as potent and orally active GPR119 agonists.

Negoro K, Yonetoku Y, Misawa-Mukai H, Hamaguchi W, Maruyama T, Yoshida S, Takeuchi M, Ohta M. Negoro K, et al. Among authors: yoshida s. Bioorg Med Chem. 2012 Sep 1;20(17):5235-46. doi: 10.1016/j.bmc.2012.06.049. Epub 2012 Jul 6. Bioorg Med Chem. 2012. PMID: 22836190

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