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Mechanotransduction of extracellular signal-regulated kinases 1 and 2 mitogen-activated protein kinase activity in smooth muscle is dependent on the extracellular matrix and regulated by matrix metalloproteinases.
Aitken KJ, Block G, Lorenzo A, Herz D, Sabha N, Dessouki O, Fung F, Szybowska M, Craig L, Bägli DJ. Aitken KJ, et al. Among authors: sabha n. Am J Pathol. 2006 Aug;169(2):459-70. doi: 10.2353/ajpath.2006.050969. Am J Pathol. 2006. PMID: 16877348 Free PMC article.
Mammalian target of rapamycin (mTOR) induces proliferation and de-differentiation responses to three coordinate pathophysiologic stimuli (mechanical strain, hypoxia, and extracellular matrix remodeling) in rat bladder smooth muscle.
Aitken KJ, Tolg C, Panchal T, Leslie B, Yu J, Elkelini M, Sabha N, Tse DJ, Lorenzo AJ, Hassouna M, Bägli DJ. Aitken KJ, et al. Among authors: sabha n. Am J Pathol. 2010 Jan;176(1):304-19. doi: 10.2353/ajpath.2010.080834. Epub 2009 Dec 17. Am J Pathol. 2010. PMID: 20019183 Free PMC article.
The role of drebrin in glioma migration and invasion.
Terakawa Y, Agnihotri S, Golbourn B, Nadi M, Sabha N, Smith CA, Croul SE, Rutka JT. Terakawa Y, et al. Among authors: sabha n. Exp Cell Res. 2013 Feb 15;319(4):517-28. doi: 10.1016/j.yexcr.2012.11.008. Epub 2012 Nov 29. Exp Cell Res. 2013. PMID: 23201135
High-grade glioma formation results from postnatal pten loss or mutant epidermal growth factor receptor expression in a transgenic mouse glioma model.
Wei Q, Clarke L, Scheidenhelm DK, Qian B, Tong A, Sabha N, Karim Z, Bock NA, Reti R, Swoboda R, Purev E, Lavoie JF, Bajenaru ML, Shannon P, Herlyn D, Kaplan D, Henkelman RM, Gutmann DH, Guha A. Wei Q, et al. Among authors: sabha n. Cancer Res. 2006 Aug 1;66(15):7429-37. doi: 10.1158/0008-5472.CAN-06-0712. Cancer Res. 2006. PMID: 16885338 Free article.
Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.
Faria CC, Golbourn BJ, Dubuc AM, Remke M, Diaz RJ, Agnihotri S, Luck A, Sabha N, Olsen S, Wu X, Garzia L, Ramaswamy V, Mack SC, Wang X, Leadley M, Reynaud D, Ermini L, Post M, Northcott PA, Pfister SM, Croul SE, Kool M, Korshunov A, Smith CA, Taylor MD, Rutka JT. Faria CC, et al. Among authors: sabha n. Cancer Res. 2015 Jan 1;75(1):134-46. doi: 10.1158/0008-5472.CAN-13-3629. Epub 2014 Nov 12. Cancer Res. 2015. PMID: 25391241
38 results