Dunford PJ - Search Results

1

The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells.

Dunford PJ, O'Donnell N, Riley JP, Williams KN, Karlsson L, Thurmond RL. Dunford PJ, et al. J Immunol. 2006 Jun 1;176(11):7062-70. doi: 10.4049/jimmunol.176.11.7062. J Immunol. 2006. PMID: 16709868

2

A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties.

Thurmond RL, Desai PJ, Dunford PJ, Fung-Leung WP, Hofstra CL, Jiang W, Nguyen S, Riley JP, Sun S, Williams KN, Edwards JP, Karlsson L. Thurmond RL, et al. Among authors: dunford pj. J Pharmacol Exp Ther. 2004 Apr;309(1):404-13. doi: 10.1124/jpet.103.061754. Epub 2004 Jan 13. J Pharmacol Exp Ther. 2004. PMID: 14722321

3

Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus.

Dunford PJ, Williams KN, Desai PJ, Karlsson L, McQueen D, Thurmond RL. Dunford PJ, et al. J Allergy Clin Immunol. 2007 Jan;119(1):176-83. doi: 10.1016/j.jaci.2006.08.034. Epub 2006 Oct 13. J Allergy Clin Immunol. 2007. PMID: 17208599

4

The histamine H(4) receptor: a novel modulator of inflammatory and immune disorders.

Zhang M, Thurmond RL, Dunford PJ. Zhang M, et al. Among authors: dunford pj. Pharmacol Ther. 2007 Mar;113(3):594-606. doi: 10.1016/j.pharmthera.2006.11.008. Epub 2006 Dec 28. Pharmacol Ther. 2007. PMID: 17275092 Review.

5

The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines.

Thurmond RL, Gelfand EW, Dunford PJ. Thurmond RL, et al. Among authors: dunford pj. Nat Rev Drug Discov. 2008 Jan;7(1):41-53. doi: 10.1038/nrd2465. Nat Rev Drug Discov. 2008. PMID: 18172439 Review.

6

The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation.

Cowden JM, Zhang M, Dunford PJ, Thurmond RL. Cowden JM, et al. Among authors: dunford pj. J Invest Dermatol. 2010 Apr;130(4):1023-33. doi: 10.1038/jid.2009.358. Epub 2009 Nov 12. J Invest Dermatol. 2010. PMID: 19907432 Free article.

7

Leukotriene A(4) hydrolase inhibition attenuates allergic airway inflammation and hyperresponsiveness.

Rao NL, Riley JP, Banie H, Xue X, Sun B, Crawford S, Lundeen KA, Yu F, Karlsson L, Fourie AM, Dunford PJ. Rao NL, et al. Among authors: dunford pj. Am J Respir Crit Care Med. 2010 May 1;181(9):899-907. doi: 10.1164/rccm.200807-1158OC. Epub 2010 Jan 28. Am J Respir Crit Care Med. 2010. PMID: 20110560

8

Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines.

Cowden JM, Riley JP, Ma JY, Thurmond RL, Dunford PJ. Cowden JM, et al. Among authors: dunford pj. Respir Res. 2010 Jun 24;11(1):86. doi: 10.1186/1465-9921-11-86. Respir Res. 2010. PMID: 20573261 Free PMC article.

9

Antagonism of the histamine H4 receptor reduces LPS-induced TNF production in vivo.

Cowden JM, Yu F, Challapalli M, Huang JF, Kim S, Fung-Leung WP, Ma JY, Riley JP, Zhang M, Dunford PJ, Thurmond RL. Cowden JM, et al. Among authors: dunford pj. Inflamm Res. 2013 Jun;62(6):599-607. doi: 10.1007/s00011-013-0612-5. Epub 2013 Mar 27. Inflamm Res. 2013. PMID: 23532396 Free PMC article.

10

The histamine H4 receptor mediates inflammation and Th17 responses in preclinical models of arthritis.

Cowden JM, Yu F, Banie H, Farahani M, Ling P, Nguyen S, Riley JP, Zhang M, Zhu J, Dunford PJ, Thurmond RL. Cowden JM, et al. Among authors: dunford pj. Ann Rheum Dis. 2014 Mar;73(3):600-8. doi: 10.1136/annrheumdis-2013-203832. Epub 2013 Oct 14. Ann Rheum Dis. 2014. PMID: 24126456 Free PMC article.

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