Narjes F - Search Results

1

Identification of thieno[3,2-b]pyrroles as allosteric inhibitors of hepatitis C virus NS5B polymerase.

Ontoria JM, Martìn Hernando JI, Malancona S, Attenni B, Stansfield I, Conte I, Ercolani C, Habermann J, Ponzi S, Di Filippo M, Koch U, Rowley M, Narjes F. Ontoria JM, et al. Among authors: narjes f. Bioorg Med Chem Lett. 2006 Aug 1;16(15):4026-30. doi: 10.1016/j.bmcl.2006.05.012. Epub 2006 May 22. Bioorg Med Chem Lett. 2006. PMID: 16714108

2

Alpha-ketoacids are potent slow binding inhibitors of the hepatitis C virus NS3 protease.

Narjes F, Brunetti M, Colarusso S, Gerlach B, Koch U, Biasiol G, Fattori D, De Francesco R, Matassa VG, Steinkühler C. Narjes F, et al. Biochemistry. 2000 Feb 22;39(7):1849-61. doi: 10.1021/bi9924260. Biochemistry. 2000. PMID: 10677236

3

Inhibition of the hepatitis C virus NS3/4A protease. The crystal structures of two protease-inhibitor complexes.

Di Marco S, Rizzi M, Volpari C, Walsh MA, Narjes F, Colarusso S, De Francesco R, Matassa VG, Sollazzo M. Di Marco S, et al. Among authors: narjes f. J Biol Chem. 2000 Mar 10;275(10):7152-7. doi: 10.1074/jbc.275.10.7152. J Biol Chem. 2000. PMID: 10702283 Free article.

4

Probing the active site of the hepatitis C virus serine protease by fluorescence resonance energy transfer.

Fattori D, Urbani A, Brunetti M, Ingenito R, Pessi A, Prendergast K, Narjes F, Matassa VG, De Francesco R, Steinkühler C. Fattori D, et al. Among authors: narjes f. J Biol Chem. 2000 May 19;275(20):15106-13. doi: 10.1074/jbc.275.20.15106. J Biol Chem. 2000. PMID: 10809747 Free article.

5

Hepatitis C virus protease inhibitors: current progress and future challenges.

Steinkühler C, Koch U, Narjes F, Matassa VG. Steinkühler C, et al. Among authors: narjes f. Curr Med Chem. 2001 Jul;8(8):919-932. doi: 10.2174/0929867013372814. Curr Med Chem. 2001. PMID: 11375758 Review.

6

A designed P1 cysteine mimetic for covalent and non-covalent inhibitors of HCV NS3 protease.

Narjes F, Koehler KF, Koch U, Gerlach B, Colarusso S, Steinkühler C, Brunetti M, Altamura S, De Francesco R, Matassa VG. Narjes F, et al. Bioorg Med Chem Lett. 2002 Feb 25;12(4):701-4. doi: 10.1016/s0960-894x(01)00842-3. Bioorg Med Chem Lett. 2002. PMID: 11844705

7

Evolution, synthesis and SAR of tripeptide alpha-ketoacid inhibitors of the hepatitis C virus NS3/NS4A serine protease.

Colarusso S, Gerlach B, Koch U, Muraglia E, Conte I, Stansfield I, Matassa VG, Narjes F. Colarusso S, et al. Among authors: narjes f. Bioorg Med Chem Lett. 2002 Feb 25;12(4):705-8. doi: 10.1016/s0960-894x(01)00843-5. Bioorg Med Chem Lett. 2002. PMID: 11844706

8

Phenethyl amides as novel noncovalent inhibitors of hepatitis C virus NS3/4A protease: discovery, initial SAR, and molecular modeling.

Colarusso S, Koch U, Gerlach B, Steinkühler C, De Francesco R, Altamura S, Matassa VG, Narjes F. Colarusso S, et al. Among authors: narjes f. J Med Chem. 2003 Jan 30;46(3):345-8. doi: 10.1021/jm025594q. J Med Chem. 2003. PMID: 12540231

9

Recent developments in the discovery of hepatitis C virus serine protease inhibitors--towards a new class of antiviral agents?

Narjes F, Koch U, Steinkühler C. Narjes F, et al. Expert Opin Investig Drugs. 2003 Feb;12(2):153-63. doi: 10.1517/13543784.12.2.153. Expert Opin Investig Drugs. 2003. PMID: 12556211 Review.

10

In vitro selection and characterization of hepatitis C virus serine protease variants resistant to an active-site peptide inhibitor.

Trozzi C, Bartholomew L, Ceccacci A, Biasiol G, Pacini L, Altamura S, Narjes F, Muraglia E, Paonessa G, Koch U, De Francesco R, Steinkuhler C, Migliaccio G. Trozzi C, et al. Among authors: narjes f. J Virol. 2003 Mar;77(6):3669-79. doi: 10.1128/jvi.77.6.3669-3679.2003. J Virol. 2003. PMID: 12610142 Free PMC article.

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