The hypersensitivity of the Chinese hamster ovary variant BL-10 to bleomycin killing is due to a lack of glutathione S-transferase-alpha activity.
Giaccia AJ, Lewis AD, Denko NC, Cholon A, Evans JW, Waldren CA, Stamato TD, Brown JM.
Giaccia AJ, et al. Among authors: denko nc.
Cancer Res. 1991 Aug 15;51(16):4463-9.
Cancer Res. 1991.
PMID: 1714344
As a means to understand the fundamental mechanisms of bleomycin cell killing, we previously isolated 19 bleomycin-sensitive mutants which represent at least six genetically distinct complementation groups (T.D. Stamato, B. Peters, P. Patil, N. Denko, R. Weinstein, …
As a means to understand the fundamental mechanisms of bleomycin cell killing, we previously isolated 19 bleomycin-sensitive mutants which r …