Trent JO - Search Results

1

CCR5 interactions with the variable 3 loop of gp120.

Napier KB, Wang ZX, Peiper SC, Trent JO. Napier KB, et al. Among authors: trent jo. J Mol Model. 2007 Jan;13(1):29-41. doi: 10.1007/s00894-006-0117-z. Epub 2006 May 24. J Mol Model. 2007. PMID: 16721558

2

Identification of ENV determinants in V3 that influence the molecular anatomy of CCR5 utilization.

Hu Q, Trent JO, Tomaras GD, Wang Z, Murray JL, Conolly SM, Navenot JM, Barry AP, Greenberg ML, Peiper SC. Hu Q, et al. Among authors: trent jo. J Mol Biol. 2000 Sep 15;302(2):359-75. doi: 10.1006/jmbi.2000.4076. J Mol Biol. 2000. PMID: 10970739

3

Molecular anatomy of CCR5 engagement by physiologic and viral chemokines and HIV-1 envelope glycoproteins: differences in primary structural requirements for RANTES, MIP-1 alpha, and vMIP-II Binding.

Navenot JM, Wang ZX, Trent JO, Murray JL, Hu QX, DeLeeuw L, Moore PS, Chang Y, Peiper SC. Navenot JM, et al. Among authors: trent jo. J Mol Biol. 2001 Nov 9;313(5):1181-93. doi: 10.1006/jmbi.2001.5086. J Mol Biol. 2001. PMID: 11700073

4

Molecular-size reduction of a potent CXCR4-chemokine antagonist using orthogonal combination of conformation- and sequence-based libraries.

Fujii N, Oishi S, Hiramatsu K, Araki T, Ueda S, Tamamura H, Otaka A, Kusano S, Terakubo S, Nakashima H, Broach JA, Trent JO, Wang ZX, Peiper SC. Fujii N, et al. Among authors: trent jo. Angew Chem Int Ed Engl. 2003 Jul 21;42(28):3251-3. doi: 10.1002/anie.200351024. Angew Chem Int Ed Engl. 2003. PMID: 12876735 No abstract available.

5

Lipid bilayer simulations of CXCR4 with inverse agonists and weak partial agonists.

Trent JO, Wang ZX, Murray JL, Shao W, Tamamura H, Fujii N, Peiper SC. Trent JO, et al. J Biol Chem. 2003 Nov 21;278(47):47136-44. doi: 10.1074/jbc.M307850200. Epub 2003 Sep 4. J Biol Chem. 2003. PMID: 12958314 Free article.

6

Synthesis of potent CXCR4 inhibitors possessing low cytotoxicity and improved biostability based on T140 derivatives.

Tamamura H, Hiramatsu K, Kusano aS, Terakubo S, Yamamoto N, Trent JO, Wang Z, Peiper SC, Nakashima H, Otaka A, Fujii N. Tamamura H, et al. Among authors: trent jo. Org Biomol Chem. 2003 Nov 7;1(21):3656-62. doi: 10.1039/b306473p. Org Biomol Chem. 2003. PMID: 14649896

7

Enhancement of the T140-based pharmacophores leads to the development of more potent and bio-stable CXCR4 antagonists.

Tamamura H, Hiramatsu K, Mizumoto M, Ueda S, Kusano S, Terakubo S, Akamatsu M, Yamamoto N, Trent JO, Wang Z, Peiper SC, Nakashima H, Otaka A, Fujii N. Tamamura H, et al. Among authors: trent jo. Org Biomol Chem. 2003 Nov 7;1(21):3663-9. doi: 10.1039/b306613b. Org Biomol Chem. 2003. PMID: 14649897

8

Topochemical exploration of potent compounds using retro-enantiomer libraries of cyclic pentapeptides.

Tamamura H, Mizumoto M, Hiramatsu K, Kusano S, Terakubo S, Yamamoto N, Trent JO, Wang Z, Peiper SC, Nakashima H, Otaka A, Fujii N. Tamamura H, et al. Among authors: trent jo. Org Biomol Chem. 2004 Apr 21;2(8):1255-7. doi: 10.1039/b401485p. Epub 2004 Mar 23. Org Biomol Chem. 2004. PMID: 15064805

9

Stereoselective synthesis of [L-Arg-L/D-3-(2-naphthyl)alanine]-type (E)-alkene dipeptide isosteres and its application to the synthesis and biological evaluation of pseudopeptide analogues of the CXCR4 antagonist FC131.

Tamamura H, Hiramatsu K, Ueda S, Wang Z, Kusano S, Terakubo S, Trent JO, Peiper SC, Yamamoto N, Nakashima H, Otaka A, Fujii N. Tamamura H, et al. Among authors: trent jo. J Med Chem. 2005 Jan 27;48(2):380-91. doi: 10.1021/jm049429h. J Med Chem. 2005. PMID: 15658852

10

Identification of novel low molecular weight CXCR4 antagonists by structural tuning of cyclic tetrapeptide scaffolds.

Tamamura H, Araki T, Ueda S, Wang Z, Oishi S, Esaka A, Trent JO, Nakashima H, Yamamoto N, Peiper SC, Otaka A, Fujii N. Tamamura H, et al. Among authors: trent jo. J Med Chem. 2005 May 5;48(9):3280-9. doi: 10.1021/jm050009h. J Med Chem. 2005. PMID: 15857134

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