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Discovery of proline sulfonamides as potent and selective hepatitis C virus NS5b polymerase inhibitors. Evidence for a new NS5b polymerase binding site.
Gopalsamy A, Chopra R, Lim K, Ciszewski G, Shi M, Curran KJ, Sukits SF, Svenson K, Bard J, Ellingboe JW, Agarwal A, Krishnamurthy G, Howe AY, Orlowski M, Feld B, O'Connell J, Mansour TS. Gopalsamy A, et al. Among authors: lim k. J Med Chem. 2006 Jun 1;49(11):3052-5. doi: 10.1021/jm060168g. J Med Chem. 2006. PMID: 16722622
Discovery of pyrano[3,4-b]indoles as potent and selective HCV NS5B polymerase inhibitors.
Gopalsamy A, Lim K, Ciszewski G, Park K, Ellingboe JW, Bloom J, Insaf S, Upeslacis J, Mansour TS, Krishnamurthy G, Damarla M, Pyatski Y, Ho D, Howe AY, Orlowski M, Feld B, O'Connell J. Gopalsamy A, et al. Among authors: lim k. J Med Chem. 2004 Dec 16;47(26):6603-8. doi: 10.1021/jm0401255. J Med Chem. 2004. PMID: 15588095
Novel and selective calcitonin-inducing agents.
Gilbert AM, Caltabiano S, Roberts D, Sum SF, Francisco GD, Lim K, Asselin M, Ellingboe JW, Kharode Y, Cannistraci A, Francis R, TrailSmith M, Gralnick D. Gilbert AM, et al. Among authors: lim k. J Med Chem. 2000 Mar 23;43(6):1223-33. doi: 10.1021/jm990558l. J Med Chem. 2000. PMID: 10737755
6,700 results