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Mdm2, but not Mdm4, protects terminally differentiated smooth muscle cells from p53-mediated caspase-3-independent cell death.
Boesten LS, Zadelaar SM, De Clercq S, Francoz S, van Nieuwkoop A, Biessen EA, Hofmann F, Feil S, Feil R, Jochemsen AG, Zurcher C, Havekes LM, van Vlijmen BJ, Marine JC. Boesten LS, et al. Among authors: jochemsen ag. Cell Death Differ. 2006 Dec;13(12):2089-98. doi: 10.1038/sj.cdd.4401973. Epub 2006 May 26. Cell Death Differ. 2006. PMID: 16729027
MDMX: a novel p53-binding protein with some functional properties of MDM2.
Shvarts A, Steegenga WT, Riteco N, van Laar T, Dekker P, Bazuine M, van Ham RC, van der Houven van Oordt W, Hateboer G, van der Eb AJ, Jochemsen AG. Shvarts A, et al. Among authors: jochemsen ag. EMBO J. 1996 Oct 1;15(19):5349-57. EMBO J. 1996. PMID: 8895579 Free PMC article.
Hdmx stabilizes Mdm2 and p53.
Stad R, Ramos YF, Little N, Grivell S, Attema J, van Der Eb AJ, Jochemsen AG. Stad R, et al. Among authors: jochemsen ag. J Biol Chem. 2000 Sep 8;275(36):28039-44. doi: 10.1074/jbc.M003496200. J Biol Chem. 2000. PMID: 10827196 Free article.
Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms.
Stad R, Little NA, Xirodimas DP, Frenk R, van der Eb AJ, Lane DP, Saville MK, Jochemsen AG. Stad R, et al. Among authors: jochemsen ag. EMBO Rep. 2001 Nov;2(11):1029-34. doi: 10.1093/embo-reports/kve227. Epub 2001 Oct 17. EMBO Rep. 2001. PMID: 11606419 Free PMC article.
Critical role for a central part of Mdm2 in the ubiquitylation of p53.
Meulmeester E, Frenk R, Stad R, de Graaf P, Marine JC, Vousden KH, Jochemsen AG. Meulmeester E, et al. Among authors: jochemsen ag. Mol Cell Biol. 2003 Jul;23(14):4929-38. doi: 10.1128/MCB.23.14.4929-4938.2003. Mol Cell Biol. 2003. PMID: 12832478 Free PMC article.
133 results