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X-ray absorption spectroscopic studies of the high-spin iron(II) active site of isopenicillin N synthase: evidence for Fe-S interaction in the enzyme-substrate complex.
Scott RA, Wang S, Eidsness MK, Kriauciunas A, Frolik CA, Chen VJ. Scott RA, et al. Among authors: kriauciunas a. Biochemistry. 1992 May 19;31(19):4596-601. doi: 10.1021/bi00134a009. Biochemistry. 1992. PMID: 1581312
Prod. Rep. 5, 129-145; Chen, V. J., Orville, A. M., Harpel, M. R., Frolik, C. A., Surerus, K. K., Munck, E., & Lipscomb, J. D. (1989) J. ...Chem. 264, 21677-21681; Ming, L.-J., Que, L., Jr., Kriauciunas, A., Frolik, C. A., & Chen, V. J. …
Prod. Rep. 5, 129-145; Chen, V. J., Orville, A. M., Harpel, M. R., Frolik, C. A., Surerus, K. K., Munck, E., & Lipscomb, J …
NMR studies of the active site of isopenicillin N synthase, a non-heme iron(II) enzyme.
Ming LJ, Que L Jr, Kriauciunas A, Frolik CA, Chen VJ. Ming LJ, et al. Among authors: kriauciunas a. Biochemistry. 1991 Dec 17;30(50):11653-9. doi: 10.1021/bi00114a007. Biochemistry. 1991. PMID: 1661145
Chem. 264, 21677-21681; Ming, L.-J., Que, L., Jr., Kriauciunas, A., Frolik, C.A., & Chen, V.J. (1990) Inorg. Chem. 26, 1111-1112]. These studies have revealed three coordinated His residues along with three sites for substrate [delta-(L-alpha-aminoadipoyl …
Chem. 264, 21677-21681; Ming, L.-J., Que, L., Jr., Kriauciunas, A., Frolik, C.A., & Chen, V.J. (1990) Inorg. Chem. …
Potent benzimidazolone based human beta(3)-adrenergic receptor agonists.
Finley DR, Bell MG, Borel AG, Bloomquist WE, Cohen ML, Heiman ML, Kriauciunas A, Matthews DP, Miles T, Neel DA, Rito CJ, Sall DJ, Shuker AJ, Stephens TW, Tinsley FC, Winter MA, Jesudason CD. Finley DR, et al. Among authors: kriauciunas a. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5691-4. doi: 10.1016/j.bmcl.2006.08.010. Epub 2006 Aug 22. Bioorg Med Chem Lett. 2006. PMID: 16931005
Combination of a Beta adrenoceptor modulator and a norepinephrine-serotonin uptake inhibitor for the treatment of obesity.
Jesudason CD, Baker JE, Bryant RD, Fisher JW, O'Farrell LS, Gaich GA, He MM, Kahl SD, Kriauciunas AV, Heiman ML, Peters MA, Rito CJ, Satterwhite JH, Tinsley FC, Trankle WG, Shuker AJ. Jesudason CD, et al. Among authors: kriauciunas av. ACS Med Chem Lett. 2011 May 23;2(8):583-6. doi: 10.1021/ml200071k. eCollection 2011 Aug 11. ACS Med Chem Lett. 2011. PMID: 24900353 Free PMC article.
Potent oxindole based human beta3 adrenergic receptor agonists.
Stevens FC, Bloomquist WE, Borel AG, Cohen ML, Droste CA, Heiman ML, Kriauciunas A, Sall DJ, Tinsley FC, Jesudason CD. Stevens FC, et al. Among authors: kriauciunas a. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6270-3. doi: 10.1016/j.bmcl.2007.09.011. Epub 2007 Sep 7. Bioorg Med Chem Lett. 2007. PMID: 17911024
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