Lundell DJ - Search Results

1

Characterization of peripheral human cannabinoid receptor (hCB2) expression and pharmacology using a novel radioligand, [35S]Sch225336.

Gonsiorek W, Hesk D, Chen SC, Kinsley D, Fine JS, Jackson JV, Bober LA, Deno G, Bian H, Fossetta J, Lunn CA, Kozlowski JA, Lavey B, Piwinski J, Narula SK, Lundell DJ, Hipkin RW. Gonsiorek W, et al. Among authors: lundell dj. J Biol Chem. 2006 Sep 22;281(38):28143-51. doi: 10.1074/jbc.M602364200. Epub 2006 Jun 5. J Biol Chem. 2006. PMID: 16754676 Free article.

2

A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo.

Lunn CA, Fine JS, Rojas-Triana A, Jackson JV, Fan X, Kung TT, Gonsiorek W, Schwarz MA, Lavey B, Kozlowski JA, Narula SK, Lundell DJ, Hipkin RW, Bober LA. Lunn CA, et al. Among authors: lundell dj. J Pharmacol Exp Ther. 2006 Feb;316(2):780-8. doi: 10.1124/jpet.105.093500. Epub 2005 Oct 28. J Pharmacol Exp Ther. 2006. PMID: 16258021

3

Triaryl bis-sulfones as a new class of cannabinoid CB2 receptor inhibitors: identification of a lead and initial SAR studies.

Lavey BJ, Kozlowski JA, Hipkin RW, Gonsiorek W, Lundell DJ, Piwinski JJ, Narula S, Lunn CA. Lavey BJ, et al. Among authors: lundell dj. Bioorg Med Chem Lett. 2005 Feb 1;15(3):783-6. doi: 10.1016/j.bmcl.2004.11.007. Bioorg Med Chem Lett. 2005. PMID: 15664857

4

Pharmacological characterization of human S1P4 using a novel radioligand, [4,5-3H]-dihydrosphingosine-1-phosphate.

Fossetta J, Deno G, Gonsiorek W, Fan X, Lavey B, Das P, Lunn C, Zavodny PJ, Lundell D, Hipkin RW. Fossetta J, et al. Br J Pharmacol. 2004 Jul;142(5):851-60. doi: 10.1038/sj.bjp.0705856. Epub 2004 Jun 14. Br J Pharmacol. 2004. PMID: 15197107 Free PMC article.

5

Biology and therapeutic potential of cannabinoid CB2 receptor inverse agonists.

Lunn CA, Reich EP, Fine JS, Lavey B, Kozlowski JA, Hipkin RW, Lundell DJ, Bober L. Lunn CA, et al. Among authors: lundell dj. Br J Pharmacol. 2008 Jan;153(2):226-39. doi: 10.1038/sj.bjp.0707480. Epub 2007 Oct 1. Br J Pharmacol. 2008. PMID: 17906679 Free PMC article. Review.

6

Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: antagonism by anandamide.

Gonsiorek W, Lunn C, Fan X, Narula S, Lundell D, Hipkin RW. Gonsiorek W, et al. Mol Pharmacol. 2000 May;57(5):1045-50. Mol Pharmacol. 2000. PMID: 10779390

7

Cannabinoid CB(2)-selective inverse agonist protects against antigen-induced bone loss.

Lunn CA, Fine J, Rojas-Triana A, Jackson JV, Lavey B, Kozlowski JA, Hipkin RW, Lundell DJ, Bober L. Lunn CA, et al. Among authors: lundell dj. Immunopharmacol Immunotoxicol. 2007;29(3-4):387-401. doi: 10.1080/08923970701674997. Immunopharmacol Immunotoxicol. 2007. PMID: 18075852

8

Non-aromatic A-ring replacement in the triaryl bis-sulfone CB2 receptor inhibitors.

Gilbert EJ, Zhou G, Wong MK, Tong L, Shankar BB, Huang C, Kelly J, Lavey BJ, McCombie SW, Chen L, Rizvi R, Dong Y, Shu Y, Kozlowski JA, Shih NY, Hipkin RW, Gonsiorek W, Malikzay A, Lunn CA, Favreau L, Lundell DJ. Gilbert EJ, et al. Among authors: lundell dj. Bioorg Med Chem Lett. 2010 Jan 15;20(2):608-11. doi: 10.1016/j.bmcl.2009.11.084. Epub 2009 Nov 22. Bioorg Med Chem Lett. 2010. PMID: 20005710

9

Expansion of SAR studies on triaryl bis sulfone cannabinoid CB2 receptor ligands.

Tong L, Shankar BB, Chen L, Rizvi R, Kelly J, Gilbert E, Huang C, Yang DY, Kozlowski JA, Shih NY, Gonsiorek W, Hipkin RW, Malikzay A, Lunn CA, Lundell DJ. Tong L, et al. Among authors: lundell dj. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6785-9. doi: 10.1016/j.bmcl.2010.08.126. Epub 2010 Aug 31. Bioorg Med Chem Lett. 2010. PMID: 20850969

10

Pharmacological analysis of calcium responses mediated by the human A3 adenosine receptor in monocyte-derived dendritic cells and recombinant cells.

Fossetta J, Jackson J, Deno G, Fan X, Du XK, Bober L, Soudé-Bermejo A, de Bouteiller O, Caux C, Lunn C, Lundell D, Palmer RK. Fossetta J, et al. Mol Pharmacol. 2003 Feb;63(2):342-50. doi: 10.1124/mol.63.2.342. Mol Pharmacol. 2003. PMID: 12527805

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