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Does the serpin PI-9 protect tumor cells?
Bots M, Offringa R, Medema JP. Bots M, et al. Among authors: medema jp. Blood. 2006 Jun 15;107(12):4974-5; author reply 4975. doi: 10.1182/blood-2006-01-0291. Blood. 2006. PMID: 16754780 Free article. No abstract available.
Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells.
Medema JP, Schuurhuis DH, Rea D, van Tongeren J, de Jong J, Bres SA, Laban S, Toes RE, Toebes M, Schumacher TN, Bladergroen BA, Ossendorp F, Kummer JA, Melief CJ, Offringa R. Medema JP, et al. J Exp Med. 2001 Sep 3;194(5):657-67. doi: 10.1084/jem.194.5.657. J Exp Med. 2001. PMID: 11535633 Free PMC article.
Granzymes at a glance.
Bots M, Medema JP. Bots M, et al. Among authors: medema jp. J Cell Sci. 2006 Dec 15;119(Pt 24):5011-4. doi: 10.1242/jcs.03239. J Cell Sci. 2006. PMID: 17158907 Review. No abstract available.
Serpins in T cell immunity.
Bots M, Medema JP. Bots M, et al. Among authors: medema jp. J Leukoc Biol. 2008 Nov;84(5):1238-47. doi: 10.1189/jlb.0208140. Epub 2008 Jul 18. J Leukoc Biol. 2008. PMID: 18641264 Review.
Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors.
Medema JP, de Jong J, Peltenburg LT, Verdegaal EM, Gorter A, Bres SA, Franken KL, Hahne M, Albar JP, Melief CJ, Offringa R. Medema JP, et al. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11515-20. doi: 10.1073/pnas.201398198. Epub 2001 Sep 18. Proc Natl Acad Sci U S A. 2001. PMID: 11562487 Free PMC article.
Strategies for immunotherapy of cancer.
Melief CJ, Toes RE, Medema JP, van der Burg SH, Ossendorp F, Offringa R. Melief CJ, et al. Among authors: medema jp. Adv Immunol. 2000;75:235-82. doi: 10.1016/s0065-2776(00)75006-1. Adv Immunol. 2000. PMID: 10879286 Review. No abstract available.
255 results