Kavanagh D - Search Results

1

Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome.

Fremeaux-Bacchi V, Moulton EA, Kavanagh D, Dragon-Durey MA, Blouin J, Caudy A, Arzouk N, Cleper R, Francois M, Guest G, Pourrat J, Seligman R, Fridman WH, Loirat C, Atkinson JP. Fremeaux-Bacchi V, et al. Among authors: kavanagh d. J Am Soc Nephrol. 2006 Jul;17(7):2017-25. doi: 10.1681/ASN.2005101051. Epub 2006 Jun 8. J Am Soc Nephrol. 2006. PMID: 16762990

2

Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome.

Kavanagh D, Kemp EJ, Mayland E, Winney RJ, Duffield JS, Warwick G, Richards A, Ward R, Goodship JA, Goodship TH. Kavanagh D, et al. J Am Soc Nephrol. 2005 Jul;16(7):2150-5. doi: 10.1681/ASN.2005010103. Epub 2005 May 25. J Am Soc Nephrol. 2005. PMID: 15917334

3

Hemolytic uremic syndrome: an example of insufficient complement regulation on self-tissue.

Atkinson JP, Liszewski MK, Richards A, Kavanagh D, Moulton EA. Atkinson JP, et al. Among authors: kavanagh d. Ann N Y Acad Sci. 2005 Nov;1056:144-52. doi: 10.1196/annals.1352.032. Ann N Y Acad Sci. 2005. PMID: 16387683 Review.

4

Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome.

Caprioli J, Noris M, Brioschi S, Pianetti G, Castelletti F, Bettinaglio P, Mele C, Bresin E, Cassis L, Gamba S, Porrati F, Bucchioni S, Monteferrante G, Fang CJ, Liszewski MK, Kavanagh D, Atkinson JP, Remuzzi G; International Registry of Recurrent and Familial HUS/TTP. Caprioli J, et al. Among authors: kavanagh d. Blood. 2006 Aug 15;108(4):1267-79. doi: 10.1182/blood-2005-10-007252. Epub 2006 Apr 18. Blood. 2006. PMID: 16621965 Free PMC article. Clinical Trial.

5

Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome.

Richards A, Kathryn Liszewski M, Kavanagh D, Fang CJ, Moulton E, Fremeaux-Bacchi V, Remuzzi G, Noris M, Goodship TH, Atkinson JP. Richards A, et al. Among authors: kavanagh d. Mol Immunol. 2007 Jan;44(1-3):111-22. doi: 10.1016/j.molimm.2006.07.004. Epub 2006 Aug 1. Mol Immunol. 2007. PMID: 16882452 Review.

6

Characterization of mutations in complement factor I (CFI) associated with hemolytic uremic syndrome.

Kavanagh D, Richards A, Noris M, Hauhart R, Liszewski MK, Karpman D, Goodship JA, Fremeaux-Bacchi V, Remuzzi G, Goodship TH, Atkinson JP. Kavanagh D, et al. Mol Immunol. 2008 Jan;45(1):95-105. doi: 10.1016/j.molimm.2007.05.004. Epub 2007 Jun 26. Mol Immunol. 2008. PMID: 17597211

7

Screening for complement system abnormalities in patients with atypical hemolytic uremic syndrome.

Kavanagh D, Richards A, Fremeaux-Bacchi V, Noris M, Goodship T, Remuzzi G, Atkinson JP. Kavanagh D, et al. Clin J Am Soc Nephrol. 2007 May;2(3):591-6. doi: 10.2215/CJN.03270906. Epub 2007 Feb 14. Clin J Am Soc Nephrol. 2007. PMID: 17699467 Review. No abstract available.

8

Complement regulatory genes and hemolytic uremic syndromes.

Kavanagh D, Richards A, Atkinson J. Kavanagh D, et al. Annu Rev Med. 2008;59:293-309. doi: 10.1146/annurev.med.59.060106.185110. Annu Rev Med. 2008. PMID: 17705684 Review.

9

Inherited complement regulatory protein deficiency predisposes to human disease in acute injury and chronic inflammatory statesthe examples of vascular damage in atypical hemolytic uremic syndrome and debris accumulation in age-related macular degeneration.

Richards A, Kavanagh D, Atkinson JP. Richards A, et al. Among authors: kavanagh d. Adv Immunol. 2007;96:141-77. doi: 10.1016/S0065-2776(07)96004-6. Adv Immunol. 2007. PMID: 17981206 Review.

10

Update on evaluating complement in hemolytic uremic syndrome.

Kavanagh D, Goodship TH. Kavanagh D, et al. Curr Opin Nephrol Hypertens. 2007 Nov;16(6):565-71. doi: 10.1097/MNH.0b013e3282f0872f. Curr Opin Nephrol Hypertens. 2007. PMID: 18089972 Review.

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