Li W - Search Results

1

Bis(7)-tacrine attenuates beta amyloid-induced neuronal apoptosis by regulating L-type calcium channels.

Fu H, Li W, Lao Y, Luo J, Lee NT, Kan KK, Tsang HW, Tsim KW, Pang Y, Li Z, Chang DC, Li M, Han Y. Fu H, et al. Among authors: li z, li w, li m. J Neurochem. 2006 Sep;98(5):1400-10. doi: 10.1111/j.1471-4159.2006.03960.x. Epub 2006 Jun 12. J Neurochem. 2006. PMID: 16771827 Free article.

2

Minocycline prevents glutamate-induced apoptosis of cerebellar granule neurons by differential regulation of p38 and Akt pathways.

Pi R, Li W, Lee NT, Chan HH, Pu Y, Chan LN, Sucher NJ, Chang DC, Li M, Han Y. Pi R, et al. Among authors: li w, li m. J Neurochem. 2004 Dec;91(5):1219-30. doi: 10.1111/j.1471-4159.2004.02796.x. J Neurochem. 2004. PMID: 15569265 Free article.

3

Novel dimeric acetylcholinesterase inhibitor bis7-tacrine, but not donepezil, prevents glutamate-induced neuronal apoptosis by blocking N-methyl-D-aspartate receptors.

Li W, Pi R, Chan HH, Fu H, Lee NT, Tsang HW, Pu Y, Chang DC, Li C, Luo J, Xiong K, Li Z, Xue H, Carlier PR, Pang Y, Tsim KW, Li M, Han Y. Li W, et al. Among authors: li c, li z, li m. J Biol Chem. 2005 May 6;280(18):18179-88. doi: 10.1074/jbc.M411085200. Epub 2005 Feb 14. J Biol Chem. 2005. PMID: 15710623 Free article.

4

Neuroprotection via inhibition of nitric oxide synthase by bis(7)-tacrine.

Li W, Lee NT, Fu H, Kan KK, Pang Y, Li M, Tsim KW, Li X, Han Y. Li W, et al. Among authors: li x, li m. Neuroreport. 2006 Apr 3;17(5):471-4. doi: 10.1097/01.wnr.0000209014.09094.72. Neuroreport. 2006. PMID: 16543809

5

Synergistic neuroprotection by bis(7)-tacrine via concurrent blockade of N-methyl-D-aspartate receptors and neuronal nitric-oxide synthase.

Li W, Xue J, Niu C, Fu H, Lam CS, Luo J, Chan HH, Xue H, Kan KK, Lee NT, Li C, Pang Y, Li M, Tsim KW, Jiang H, Chen K, Li X, Han Y. Li W, et al. Among authors: li c, li x, li m. Mol Pharmacol. 2007 May;71(5):1258-67. doi: 10.1124/mol.106.029108. Epub 2007 Feb 13. Mol Pharmacol. 2007. PMID: 17299028

6

Mitochondrial proteomic analysis and characterization of the intracellular mechanisms of bis(7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured neurons.

Fu H, Li W, Liu Y, Lao Y, Liu W, Chen C, Yu H, Lee NT, Chang DC, Li P, Pang Y, Tsim KW, Li M, Han Y. Fu H, et al. Among authors: li w, li m, li p. J Proteome Res. 2007 Jul;6(7):2435-46. doi: 10.1021/pr060615g. Epub 2007 May 27. J Proteome Res. 2007. PMID: 17530875

7

Novel dimeric bis(7)-tacrine proton-dependently inhibits NMDA-activated currents.

Luo J, Li W, Liu Y, Zhang W, Fu H, Lee NT, Yu H, Pang Y, Huang P, Xia J, Li ZW, Li C, Han Y. Luo J, et al. Among authors: li zw, li c, li w. Biochem Biophys Res Commun. 2007 Sep 21;361(2):505-9. doi: 10.1016/j.bbrc.2007.07.043. Epub 2007 Jul 20. Biochem Biophys Res Commun. 2007. PMID: 17655827

8

Promising anti-Alzheimer's dimer bis(7)-tacrine reduces beta-amyloid generation by directly inhibiting BACE-1 activity.

Fu H, Li W, Luo J, Lee NT, Li M, Tsim KW, Pang Y, Youdim MB, Han Y. Fu H, et al. Among authors: li w, li m. Biochem Biophys Res Commun. 2008 Feb 15;366(3):631-6. doi: 10.1016/j.bbrc.2007.11.068. Epub 2007 Nov 26. Biochem Biophys Res Commun. 2008. PMID: 18039469

9

Mecamylamine prevents neuronal apoptosis induced by glutamate and low potassium via differential anticholinergic-independent mechanisms.

Fu H, Dou J, Li W, Luo J, Li KC, Lam CS, Lee NT, Li M, Han Y. Fu H, et al. Among authors: li w, li m, li kc. Neuropharmacology. 2008 Mar;54(4):755-65. doi: 10.1016/j.neuropharm.2007.12.003. Epub 2007 Dec 23. Neuropharmacology. 2008. PMID: 18222492

10

Bis(7)-tacrine, a promising anti-Alzheimer's dimer, affords dose- and time-dependent neuroprotection against transient focal cerebral ischemia.

Zhao Y, Li W, Chow PC, Lau DT, Lee NT, Pang Y, Zhang X, Wang X, Han Y. Zhao Y, et al. Among authors: li w. Neurosci Lett. 2008 Jul 11;439(2):160-4. doi: 10.1016/j.neulet.2008.05.007. Epub 2008 May 8. Neurosci Lett. 2008. PMID: 18515007

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