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Suppression of sorbitol dependence in a strain bearing a mutation in the SRB1/PSA1/VIG9 gene encoding GDP-mannose pyrophosphorylase by PDE2 overexpression suggests a role for the Ras/cAMP signal-transduction pathway in the control of yeast cell-wall biogenesis.
Tomlin GC, Hamilton GE, Gardner DCJ, Walmsley RM, Stateva LI, Oliver SG. Tomlin GC, et al. Microbiology (Reading). 2000 Sep;146 ( Pt 9):2133-2146. doi: 10.1099/00221287-146-9-2133. Microbiology (Reading). 2000. PMID: 10974101 Free article.