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Page 1
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors.
Gasparre G, Porcelli AM, Bonora E, Pennisi LF, Toller M, Iommarini L, Ghelli A, Moretti M, Betts CM, Martinelli GN, Ceroni AR, Curcio F, Carelli V, Rugolo M, Tallini G, Romeo G. Gasparre G, et al. Among authors: tallini g. Proc Natl Acad Sci U S A. 2007 May 22;104(21):9001-6. doi: 10.1073/pnas.0703056104. Epub 2007 May 15. Proc Natl Acad Sci U S A. 2007. PMID: 17517629 Free PMC article.
The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization.
Porcelli AM, Ghelli A, Ceccarelli C, Lang M, Cenacchi G, Capristo M, Pennisi LF, Morra I, Ciccarelli E, Melcarne A, Bartoletti-Stella A, Salfi N, Tallini G, Martinuzzi A, Carelli V, Attimonelli M, Rugolo M, Romeo G, Gasparre G. Porcelli AM, et al. Among authors: tallini g. Hum Mol Genet. 2010 Mar 15;19(6):1019-32. doi: 10.1093/hmg/ddp566. Epub 2009 Dec 22. Hum Mol Genet. 2010. PMID: 20028790
Molecular features of thyroid oncocytic tumors.
Gasparre G, Bonora E, Tallini G, Romeo G. Gasparre G, et al. Among authors: tallini g. Mol Cell Endocrinol. 2010 May 28;321(1):67-76. doi: 10.1016/j.mce.2010.02.022. Epub 2010 Feb 23. Mol Cell Endocrinol. 2010. PMID: 20184940 Review.
Genomic profiling of mitochondrion-rich breast carcinoma: chromosomal changes may be relevant for mitochondria accumulation and tumour biology.
Geyer FC, de Biase D, Lambros MB, Ragazzi M, Lopez-Garcia MA, Natrajan R, Mackay A, Kurelac I, Gasparre G, Ashworth A, Eusebi V, Reis-Filho JS, Tallini G. Geyer FC, et al. Among authors: tallini g. Breast Cancer Res Treat. 2012 Feb;132(1):15-28. doi: 10.1007/s10549-011-1504-4. Epub 2011 Apr 21. Breast Cancer Res Treat. 2012. PMID: 21509527
Somatic complex I disruptive mitochondrial DNA mutations are modifiers of tumorigenesis that correlate with low genomic instability in pituitary adenomas.
Kurelac I, MacKay A, Lambros MB, Di Cesare E, Cenacchi G, Ceccarelli C, Morra I, Melcarne A, Morandi L, Calabrese FM, Attimonelli M, Tallini G, Reis-Filho JS, Gasparre G. Kurelac I, et al. Among authors: tallini g. Hum Mol Genet. 2013 Jan 15;22(2):226-38. doi: 10.1093/hmg/dds422. Epub 2012 Oct 9. Hum Mol Genet. 2013. PMID: 23049073
High-resolution genomic profiling of thyroid lesions uncovers preferential copy number gains affecting mitochondrial biogenesis loci in the oncocytic variants.
Kurelac I, de Biase D, Calabrese C, Ceccarelli C, Ng CK, Lim R, MacKay A, Weigelt B, Porcelli AM, Reis-Filho JS, Tallini G, Gasparre G. Kurelac I, et al. Among authors: tallini g. Am J Cancer Res. 2015 May 15;5(6):1954-71. eCollection 2015. Am J Cancer Res. 2015. PMID: 26269756 Free PMC article.
293 results