Nordlund HR - Search Results

1

Controlling quaternary structure assembly: subunit interface engineering and crystal structure of dual chain avidin.

Hytönen VP, Hörhä J, Airenne TT, Niskanen EA, Helttunen KJ, Johnson MS, Salminen TA, Kulomaa MS, Nordlund HR. Hytönen VP, et al. Among authors: nordlund hr. J Mol Biol. 2006 Jun 23;359(5):1352-63. doi: 10.1016/j.jmb.2006.04.044. Epub 2006 May 6. J Mol Biol. 2006. PMID: 16787776

2

Enhancing the thermal stability of avidin. Introduction of disulfide bridges between subunit interfaces.

Nordlund HR, Laitinen OH, Uotila ST, Nyholm T, Hytönen VP, Slotte JP, Kulomaa MS. Nordlund HR, et al. J Biol Chem. 2003 Jan 24;278(4):2479-83. doi: 10.1074/jbc.M210721200. Epub 2002 Nov 20. J Biol Chem. 2003. PMID: 12446662 Free article.

3

Rational design of an active avidin monomer.

Laitinen OH, Nordlund HR, Hytönen VP, Uotila ST, Marttila AT, Savolainen J, Airenne KJ, Livnah O, Bayer EA, Wilchek M, Kulomaa MS. Laitinen OH, et al. Among authors: nordlund hr. J Biol Chem. 2003 Feb 7;278(6):4010-4. doi: 10.1074/jbc.M205844200. Epub 2002 Nov 27. J Biol Chem. 2003. PMID: 12458212 Free article.

4

Introduction of histidine residues into avidin subunit interfaces allows pH-dependent regulation of quaternary structure and biotin binding.

Nordlund HR, Hytönen VP, Laitinen OH, Uotila ST, Niskanen EA, Savolainen J, Porkka E, Kulomaa MS. Nordlund HR, et al. FEBS Lett. 2003 Dec 18;555(3):449-54. doi: 10.1016/s0014-5793(03)01302-4. FEBS Lett. 2003. PMID: 14675754 Free article.

5

Construction of a dual chain pseudotetrameric chicken avidin by combining two circularly permuted avidins.

Nordlund HR, Laitinen OH, Hytönen VP, Uotila ST, Porkka E, Kulomaa MS. Nordlund HR, et al. J Biol Chem. 2004 Aug 27;279(35):36715-9. doi: 10.1074/jbc.M403496200. Epub 2004 May 6. J Biol Chem. 2004. PMID: 15131113 Free article.

6

Design and construction of highly stable, protease-resistant chimeric avidins.

Hytönen VP, Määttä JA, Nyholm TK, Livnah O, Eisenberg-Domovich Y, Hyre D, Nordlund HR, Hörhä J, Niskanen EA, Paldanius T, Kulomaa T, Porkka EJ, Stayton PS, Laitinen OH, Kulomaa MS. Hytönen VP, et al. Among authors: nordlund hr. J Biol Chem. 2005 Mar 18;280(11):10228-33. doi: 10.1074/jbc.M414196200. Epub 2005 Jan 13. J Biol Chem. 2005. PMID: 15649900 Free article.

7

Novel avidin-like protein from a root nodule symbiotic bacterium, Bradyrhizobium japonicum.

Nordlund HR, Hytönen VP, Laitinen OH, Kulomaa MS. Nordlund HR, et al. J Biol Chem. 2005 Apr 8;280(14):13250-5. doi: 10.1074/jbc.M414336200. Epub 2005 Jan 28. J Biol Chem. 2005. PMID: 15695809 Free article.

8

Chicken genome analysis reveals novel genes encoding biotin-binding proteins related to avidin family.

Niskanen EA, Hytönen VP, Grapputo A, Nordlund HR, Kulomaa MS, Laitinen OH. Niskanen EA, et al. Among authors: nordlund hr. BMC Genomics. 2005 Mar 18;6:41. doi: 10.1186/1471-2164-6-41. BMC Genomics. 2005. PMID: 15777476 Free PMC article.

9

Tetravalent single-chain avidin: from subunits to protein domains via circularly permuted avidins.

Nordlund HR, Hytönen VP, Hörhä J, Määttä JA, White DJ, Halling K, Porkka EJ, Slotte JP, Laitinen OH, Kulomaa MS. Nordlund HR, et al. Biochem J. 2005 Dec 15;392(Pt 3):485-91. doi: 10.1042/BJ20051038. Biochem J. 2005. PMID: 16092919 Free PMC article.

10

Dual-affinity avidin molecules.

Hytönen VP, Nordlund HR, Hörhä J, Nyholm TK, Hyre DE, Kulomaa T, Porkka EJ, Marttila AT, Stayton PS, Laitinen OH, Kulomaa MS. Hytönen VP, et al. Among authors: nordlund hr. Proteins. 2005 Nov 15;61(3):597-607. doi: 10.1002/prot.20604. Proteins. 2005. PMID: 16175628

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