Fazzone W - Search Results

1

Cyclin D1 and epidermal growth factor polymorphisms associated with survival in patients with advanced colorectal cancer treated with Cetuximab.

Zhang W, Gordon M, Press OA, Rhodes K, Vallböhmer D, Yang DY, Park D, Fazzone W, Schultheis A, Sherrod AE, Iqbal S, Groshen S, Lenz HJ. Zhang W, et al. Among authors: fazzone w. Pharmacogenet Genomics. 2006 Jul;16(7):475-83. doi: 10.1097/01.fpc.0000220562.67595.a5. Pharmacogenet Genomics. 2006. PMID: 16788380 Clinical Trial.

2

Thymidylate synthase haplotype is associated with tumor recurrence in stage II and stage III colon cancer.

Lurje G, Zhang W, Yang D, Groshen S, Hendifar AE, Husain H, Nagashima F, Chang HM, Fazzone W, Ladner RD, Pohl A, Ning Y, Iqbal S, El-Khoueiry A, Lenz HJ. Lurje G, et al. Among authors: fazzone w. Pharmacogenet Genomics. 2008 Feb;18(2):161-8. doi: 10.1097/FPC.0b013e3282f4aea6. Pharmacogenet Genomics. 2008. PMID: 18192902

3

ABCB1, SLCO1B1 and UGT1A1 gene polymorphisms are associated with toxicity in metastatic colorectal cancer patients treated with first-line irinotecan.

Rhodes KE, Zhang W, Yang D, Press OA, Gordon M, Vallböhmer D, Schultheis AM, Lurje G, Ladner RD, Fazzone W, Iqbal S, Lenz HJ. Rhodes KE, et al. Among authors: fazzone w. Drug Metab Lett. 2007 Jan;1(1):23-30. doi: 10.2174/187231207779814328. Drug Metab Lett. 2007. PMID: 19356014 Clinical Trial.

4

Molecular determinants of irinotecan efficacy.

Vallböhmer D, Iqbal S, Yang DY, Rhodes KE, Zhang W, Gordon M, Fazzone W, Schultheis AM, Sherrod AE, Danenberg KD, Lenz HJ. Vallböhmer D, et al. Among authors: fazzone w. Int J Cancer. 2006 Nov 15;119(10):2435-42. doi: 10.1002/ijc.22129. Int J Cancer. 2006. PMID: 16894565

5

Association of methylenetetrahydrofolate reductase gene polymorphisms and sex-specific survival in patients with metastatic colon cancer.

Zhang W, Press OA, Haiman CA, Yang DY, Gordon MA, Fazzone W, El-Khoueiry A, Iqbal S, Sherrod AE, Lurje G, Lenz HJ. Zhang W, et al. Among authors: fazzone w. J Clin Oncol. 2007 Aug 20;25(24):3726-31. doi: 10.1200/JCO.2007.11.4710. J Clin Oncol. 2007. PMID: 17704422

6

DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines.

LaBonte MJ, Wilson PM, Fazzone W, Groshen S, Lenz HJ, Ladner RD. LaBonte MJ, et al. Among authors: fazzone w. BMC Med Genomics. 2009 Nov 30;2:67. doi: 10.1186/1755-8794-2-67. BMC Med Genomics. 2009. PMID: 19948057 Free PMC article.

7

A phase I/II trial of vorinostat in combination with 5-fluorouracil in patients with metastatic colorectal cancer who previously failed 5-FU-based chemotherapy.

Wilson PM, El-Khoueiry A, Iqbal S, Fazzone W, LaBonte MJ, Groshen S, Yang D, Danenberg KD, Cole S, Kornacki M, Ladner RD, Lenz HJ. Wilson PM, et al. Among authors: fazzone w. Cancer Chemother Pharmacol. 2010 Apr;65(5):979-88. doi: 10.1007/s00280-009-1236-x. Cancer Chemother Pharmacol. 2010. PMID: 20062993 Clinical Trial.

8

The dual EGFR/HER2 inhibitor lapatinib synergistically enhances the antitumor activity of the histone deacetylase inhibitor panobinostat in colorectal cancer models.

LaBonte MJ, Wilson PM, Fazzone W, Russell J, Louie SG, El-Khoueiry A, Lenz HJ, Ladner RD. LaBonte MJ, et al. Among authors: fazzone w. Cancer Res. 2011 May 15;71(10):3635-48. doi: 10.1158/0008-5472.CAN-10-2430. Epub 2011 Apr 4. Cancer Res. 2011. PMID: 21464044 Free PMC article.

9

Histone deacetylase inhibitors suppress thymidylate synthase gene expression and synergize with the fluoropyrimidines in colon cancer cells.

Fazzone W, Wilson PM, Labonte MJ, Lenz HJ, Ladner RD. Fazzone W, et al. Int J Cancer. 2009 Jul 15;125(2):463-73. doi: 10.1002/ijc.24403. Int J Cancer. 2009. PMID: 19384949

10

The dual EGFR/HER-2 tyrosine kinase inhibitor lapatinib sensitizes colon and gastric cancer cells to the irinotecan active metabolite SN-38.

LaBonte MJ, Manegold PC, Wilson PM, Fazzone W, Louie SG, Lenz HJ, Ladner RD. LaBonte MJ, et al. Among authors: fazzone w. Int J Cancer. 2009 Dec 15;125(12):2957-69. doi: 10.1002/ijc.24658. Int J Cancer. 2009. PMID: 19536776

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