Shaw JP - Search Results

1

Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma.

Pomel V, Klicic J, Covini D, Church DD, Shaw JP, Roulin K, Burgat-Charvillon F, Valognes D, Camps M, Chabert C, Gillieron C, Françon B, Perrin D, Leroy D, Gretener D, Nichols A, Vitte PA, Carboni S, Rommel C, Schwarz MK, Rückle T. Pomel V, et al. Among authors: shaw jp. J Med Chem. 2006 Jun 29;49(13):3857-71. doi: 10.1021/jm0601598. J Med Chem. 2006. PMID: 16789742

2

Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

Camps M, Rückle T, Ji H, Ardissone V, Rintelen F, Shaw J, Ferrandi C, Chabert C, Gillieron C, Françon B, Martin T, Gretener D, Perrin D, Leroy D, Vitte PA, Hirsch E, Wymann MP, Cirillo R, Schwarz MK, Rommel C. Camps M, et al. Nat Med. 2005 Sep;11(9):936-43. doi: 10.1038/nm1284. Epub 2005 Aug 28. Nat Med. 2005. PMID: 16127437 Free article.

3

Identification and characterization of novel small molecules as potent inhibitors of the plasmodial calcium-dependent protein kinase 1.

Lemercier G, Fernandez-Montalvan A, Shaw JP, Kugelstadt D, Bomke J, Domostoj M, Schwarz MK, Scheer A, Kappes B, Leroy D. Lemercier G, et al. Among authors: shaw jp. Biochemistry. 2009 Jul 14;48(27):6379-89. doi: 10.1021/bi9005122. Biochemistry. 2009. PMID: 19507895

4

Substrate recognition domains within extracellular signal-regulated kinase mediate binding and catalytic activation of mitogen-activated protein kinase phosphatase-3.

Nichols A, Camps M, Gillieron C, Chabert C, Brunet A, Wilsbacher J, Cobb M, Pouyssegur J, Shaw JP, Arkinstall S. Nichols A, et al. Among authors: shaw jp. J Biol Chem. 2000 Aug 11;275(32):24613-21. doi: 10.1074/jbc.M001515200. J Biol Chem. 2000. PMID: 10811804 Free article.

5

Glycosaminoglycan analogs as a novel anti-inflammatory strategy.

Severin IC, Soares A, Hantson J, Teixeira M, Sachs D, Valognes D, Scheer A, Schwarz MK, Wells TN, Proudfoot AE, Shaw J. Severin IC, et al. Front Immunol. 2012 Oct 16;3:293. doi: 10.3389/fimmu.2012.00293. eCollection 2012. Front Immunol. 2012. PMID: 23087686 Free PMC article.

6

The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.

Shaw JP, Johnson Z, Borlat F, Zwahlen C, Kungl A, Roulin K, Harrenga A, Wells TN, Proudfoot AE. Shaw JP, et al. Structure. 2004 Nov;12(11):2081-93. doi: 10.1016/j.str.2004.08.014. Structure. 2004. PMID: 15530372 Free article.

7

The p110 delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors.

Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Rückle T, Schwarz MK, Shokat KM, Shaw JP, Williams RL. Berndt A, et al. Among authors: shaw jp. Nat Chem Biol. 2010 Feb;6(2):117-24. doi: 10.1038/nchembio.293. Nat Chem Biol. 2010. PMID: 20081827 Free PMC article.

8

The p110delta structure: mechanisms for selectivity and potency of new PI(3)K inhibitors.

Berndt A, Miller S, Williams O, Le DD, Houseman BT, Pacold JI, Gorrec F, Hon WC, Liu Y, Rommel C, Gaillard P, Rückle T, Schwarz MK, Shokat KM, Shaw JP, Williams RL. Berndt A, et al. Among authors: shaw jp. Nat Chem Biol. 2010 Mar;6(3):244. doi: 10.1038/nchembio0310-244b. Nat Chem Biol. 2010. PMID: 20154668 No abstract available.

9

Identification of the pharmacophore of the CC chemokine-binding proteins Evasin-1 and -4 using phage display.

Bonvin P, Dunn SM, Rousseau F, Dyer DP, Shaw J, Power CA, Handel TM, Proudfoot AEI. Bonvin P, et al. J Biol Chem. 2014 Nov 14;289(46):31846-31855. doi: 10.1074/jbc.M114.599233. Epub 2014 Sep 29. J Biol Chem. 2014. PMID: 25266725 Free PMC article.

10

Structural basis of chemokine sequestration by a tick chemokine binding protein: the crystal structure of the complex between Evasin-1 and CCL3.

Dias JM, Losberger C, Déruaz M, Power CA, Proudfoot AE, Shaw JP. Dias JM, et al. Among authors: shaw jp. PLoS One. 2009 Dec 30;4(12):e8514. doi: 10.1371/journal.pone.0008514. PLoS One. 2009. PMID: 20041127 Free PMC article.

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