Sousa EH - Search Results

1

A proximal arginine R206 participates in switching of the Bradyrhizobium japonicum FixL oxygen sensor.

Gilles-Gonzalez MA, Caceres AI, Sousa EH, Tomchick DR, Brautigam C, Gonzalez C, Machius M. Gilles-Gonzalez MA, et al. Among authors: sousa eh. J Mol Biol. 2006 Jun 30;360(1):80-9. doi: 10.1016/j.jmb.2006.04.054. Epub 2006 May 11. J Mol Biol. 2006. PMID: 16813836

2

Oxygen blocks the reaction of the FixL-FixJ complex with ATP but does not influence binding of FixJ or ATP to FixL.

Sousa EH, Gonzalez G, Gilles-Gonzalez MA. Sousa EH, et al. Biochemistry. 2005 Nov 22;44(46):15359-65. doi: 10.1021/bi051661h. Biochemistry. 2005. PMID: 16285740

3

A memory of oxygen binding explains the dose response of the heme-based sensor FixL.

Sousa EH, Tuckerman JR, Gonzalez G, Gilles-Gonzalez MA. Sousa EH, et al. Biochemistry. 2007 May 29;46(21):6249-57. doi: 10.1021/bi7003334. Epub 2007 May 8. Biochemistry. 2007. PMID: 17487983

4

Oxygen-sensing histidine-protein kinases: assays of ligand binding and turnover of response-regulator substrates.

Gilles-Gonzalez MA, Gonzalez G, Sousa EH, Tuckerman J. Gilles-Gonzalez MA, et al. Among authors: sousa eh. Methods Enzymol. 2008;437:173-89. doi: 10.1016/S0076-6879(07)37010-9. Methods Enzymol. 2008. PMID: 18433629 Review.

5

DosT and DevS are oxygen-switched kinases in Mycobacterium tuberculosis.

Sousa EH, Tuckerman JR, Gonzalez G, Gilles-Gonzalez MA. Sousa EH, et al. Protein Sci. 2007 Aug;16(8):1708-19. doi: 10.1110/ps.072897707. Epub 2007 Jun 28. Protein Sci. 2007. PMID: 17600145 Free PMC article.

6

Drug discovery targeting heme-based sensors and their coupled activities.

Sousa EH, Lopes LG, Gonzalez G, Gilles-Gonzalez MA. Sousa EH, et al. J Inorg Biochem. 2017 Feb;167:12-20. doi: 10.1016/j.jinorgbio.2016.11.022. Epub 2016 Nov 20. J Inorg Biochem. 2017. PMID: 27893989 Review.

7

Nitro-imidazole-based ruthenium complexes with antioxidant and anti-inflammatory activities.

Sasahara GL, Gouveia Júnior FS, Rodrigues RO, Zampieri DS, Fonseca SGDC, Gonçalves RCR, Athaydes BR, Kitagawa RR, Santos FA, Sousa EHS, Nagao-Dias AT, Lopes LGF. Sasahara GL, et al. J Inorg Biochem. 2020 May;206:111048. doi: 10.1016/j.jinorgbio.2020.111048. Epub 2020 Feb 24. J Inorg Biochem. 2020. PMID: 32151873

8

A divergent mode of activation of a nitrosyl iron complex with unusual antiangiogenic activity.

Carvalho EM, Ridnour LA, Júnior FSG, Cabral PHB, do Nascimento NRF, Wink DA, Franco DW, de Medeiros MJC, de Lima Pontes D, Longhinotti E, de Freitas Paulo T, Bernardes-Génisson V, Chauvin R, Sousa EHS, Lopes LGF. Carvalho EM, et al. J Inorg Biochem. 2020 Sep;210:111133. doi: 10.1016/j.jinorgbio.2020.111133. Epub 2020 Jun 20. J Inorg Biochem. 2020. PMID: 32619898 Free PMC article.

9

Isoniazid metal complex reactivity and insights for a novel anti-tuberculosis drug design.

Sousa EH, Basso LA, Santos DS, Diógenes IC, Longhinotti E, Lopes LG, Moreira Ide S. Sousa EH, et al. J Biol Inorg Chem. 2012 Feb;17(2):275-83. doi: 10.1007/s00775-011-0848-x. Epub 2011 Sep 28. J Biol Inorg Chem. 2012. PMID: 21952749

10

[Fe(CN)5(isoniazid)](3-): an iron isoniazid complex with redox behavior implicated in tuberculosis therapy.

Sousa EH, de Mesquita Vieira FG, Butler JS, Basso LA, Santiago DS, Diógenes IC, Lopes LG, Sadler PJ. Sousa EH, et al. J Inorg Biochem. 2014 Nov;140:236-44. doi: 10.1016/j.jinorgbio.2014.08.002. Epub 2014 Aug 12. J Inorg Biochem. 2014. PMID: 25189361

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