Bol DK - Search Results

1

Constitutively active receptor tyrosine kinases as oncogenes in preclinical models for cancer therapeutics.

Kellar KA, Lorenzi MV, Ho CP, You D, Wen ML, Ryseck RP, Oppenheimer S, Fink BE, Vite GD, Rowley BR, Yu C, Bol DK, Lee FY, Wong TW. Kellar KA, et al. Among authors: bol dk. Mol Cancer Ther. 2006 Jun;5(6):1571-6. doi: 10.1158/1535-7163.MCT-06-0078. Mol Cancer Ther. 2006. PMID: 16818516

2

Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor.

Carboni JM, Lee AV, Hadsell DL, Rowley BR, Lee FY, Bol DK, Camuso AE, Gottardis M, Greer AF, Ho CP, Hurlburt W, Li A, Saulnier M, Velaparthi U, Wang C, Wen ML, Westhouse RA, Wittman M, Zimmermann K, Rupnow BA, Wong TW. Carboni JM, et al. Among authors: bol dk. Cancer Res. 2005 May 1;65(9):3781-7. doi: 10.1158/0008-5472.CAN-04-4602. Cancer Res. 2005. PMID: 15867374

3

Apoptotic and cytostatic farnesyltransferase inhibitors have distinct pharmacology and efficacy profiles in tumor models.

Manne V, Lee FY, Bol DK, Gullo-Brown J, Fairchild CR, Lombardo LJ, Smykla RA, Vite GD, Wen ML, Yu C, Wong TW, Hunt JT. Manne V, et al. Among authors: bol dk. Cancer Res. 2004 Jun 1;64(11):3974-80. doi: 10.1158/0008-5472.CAN-03-3849. Cancer Res. 2004. PMID: 15173010

4

Discovery of aminothiazole inhibitors of cyclin-dependent kinase 2: synthesis, X-ray crystallographic analysis, and biological activities.

Kim KS, Kimball SD, Misra RN, Rawlins DB, Hunt JT, Xiao HY, Lu S, Qian L, Han WC, Shan W, Mitt T, Cai ZW, Poss MA, Zhu H, Sack JS, Tokarski JS, Chang CY, Pavletich N, Kamath A, Humphreys WG, Marathe P, Bursuker I, Kellar KA, Roongta U, Batorsky R, Mulheron JG, Bol D, Fairchild CR, Lee FY, Webster KR. Kim KS, et al. J Med Chem. 2002 Aug 29;45(18):3905-27. doi: 10.1021/jm0201520. J Med Chem. 2002. PMID: 12190313

5

Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development.

Bol DK, Rowley RB, Ho CP, Pilz B, Dell J, Swerdel M, Kiguchi K, Muga S, Klein R, Fischer SM. Bol DK, et al. Cancer Res. 2002 May 1;62(9):2516-21. Cancer Res. 2002. PMID: 11980643

6

Constitutive expression of insulin-like growth factor-1 in epidermal basal cells of transgenic mice leads to spontaneous tumor promotion.

DiGiovanni J, Bol DK, Wilker E, Beltrán L, Carbajal S, Moats S, Ramirez A, Jorcano J, Kiguchi K. DiGiovanni J, et al. Among authors: bol dk. Cancer Res. 2000 Mar 15;60(6):1561-70. Cancer Res. 2000. PMID: 10749124

7

Targeted expression of c-Src in epidermal basal cells leads to enhanced skin tumor promotion, malignant progression, and metastasis.

Matsumoto T, Jiang J, Kiguchi K, Ruffino L, Carbajal S, Beltrán L, Bol DK, Rosenberg MP, DiGiovanni J. Matsumoto T, et al. Among authors: bol dk. Cancer Res. 2003 Aug 15;63(16):4819-28. Cancer Res. 2003. PMID: 12941801

8

Overexpression of insulin-like growth factor-1 induces hyperplasia, dermal abnormalities, and spontaneous tumor formation in transgenic mice.

Bol DK, Kiguchi K, Gimenez-Conti I, Rupp T, DiGiovanni J. Bol DK, et al. Oncogene. 1997 Apr 10;14(14):1725-34. doi: 10.1038/sj.onc.1201011. Oncogene. 1997. PMID: 9135074

9

Enhancement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice.

Wilker E, Bol D, Kiguchi K, Rupp T, Beltrán L, DiGiovanni J. Wilker E, et al. Mol Carcinog. 1999 Jun;25(2):122-31. doi: 10.1002/(sici)1098-2744(199906)25:2<122::aid-mc7>3.0.co;2-8. Mol Carcinog. 1999. PMID: 10365914

10

Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development.

Kiguchi K, Bol D, Carbajal S, Beltrán L, Moats S, Chan K, Jorcano J, DiGiovanni J. Kiguchi K, et al. Oncogene. 2000 Aug 31;19(37):4243-54. doi: 10.1038/sj.onc.1203778. Oncogene. 2000. PMID: 10980598

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