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Page 1
The value of alternative testing for neurotoxicity in the context of regulatory needs.
Coecke S, Eskes C, Gartlon J, Kinsner A, Price A, van Vliet E, Prieto P, Boveri M, Bremer S, Adler S, Pellizzer C, Wendel A, Hartung T. Coecke S, et al. Among authors: gartlon j. Environ Toxicol Pharmacol. 2006 Feb;21(2):153-67. doi: 10.1016/j.etap.2005.07.006. Epub 2005 Aug 24. Environ Toxicol Pharmacol. 2006. PMID: 21783653
Pre-clinical characterisation of E2814, a high-affinity antibody targeting the microtubule-binding repeat domain of tau for passive immunotherapy in Alzheimer's disease.
Roberts M, Sevastou I, Imaizumi Y, Mistry K, Talma S, Dey M, Gartlon J, Ochiai H, Zhou Z, Akasofu S, Tokuhara N, Ogo M, Aoyama M, Aoyagi H, Strand K, Sajedi E, Agarwala KL, Spidel J, Albone E, Horie K, Staddon JM, de Silva R. Roberts M, et al. Among authors: gartlon j. Acta Neuropathol Commun. 2020 Feb 4;8(1):13. doi: 10.1186/s40478-020-0884-2. Acta Neuropathol Commun. 2020. PMID: 32019610 Free PMC article.
Pharmacological characterization of N-[(2S)-5-(6-fluoro-3-pyridinyl)-2, 3-dihydro-1H-inden-2-yl]-2-propanesulfonamide: a novel, clinical AMPA receptor positive allosteric modulator.
Ward SE, Beswick P, Calcinaghi N, Dawson LA, Gartlon J, Graziani F, Jones DN, Lacroix L, Selina Mok MH, Oliosi B, Pardoe J, Starr K, Woolley ML, Harries MH. Ward SE, et al. Among authors: gartlon j. Br J Pharmacol. 2017 Mar;174(5):370-385. doi: 10.1111/bph.13696. Epub 2017 Jan 31. Br J Pharmacol. 2017. PMID: 28009436 Free PMC article.
Identification and optimisation of a series of tetrahydrobenzotriazoles as metabotropic glutamate receptor 5-selective positive allosteric modulators that improve performance in a preclinical model of cognition.
Ellard JM, Madin A, Philps O, Hopkin M, Henderson S, Birch L, O'Connor D, Arai T, Takase K, Morgan L, Reynolds D, Talma S, Howley E, Powney B, Payne AH, Hall A, Gartlon JE, Dawson LA, Castro L, Atkinson PJ. Ellard JM, et al. Among authors: gartlon je. Bioorg Med Chem Lett. 2015 Dec 15;25(24):5792-6. doi: 10.1016/j.bmcl.2015.10.050. Epub 2015 Oct 17. Bioorg Med Chem Lett. 2015. PMID: 26531152
25 results