Kostakis IK - Search Results

1

Synthesis and antiproliferative activity of substituted benzopyranoisoindoles: a new class of cytotoxic compounds.

Hadjipavlou C, Kostakis IK, Pouli N, Marakos P, Pratsinis H, Kletsas D. Hadjipavlou C, et al. Among authors: kostakis ik. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4822-5. doi: 10.1016/j.bmcl.2006.06.074. Epub 2006 Jul 7. Bioorg Med Chem Lett. 2006. PMID: 16824751

2

Synthesis and cytotoxic activity of 2-dialkylaminoethylamino substituted xanthenone and thioxanthenone derivatives.

Kostakis I, Ghirtis K, Pouli N, Marakos P, Skaltsounis AL, Leonce S, Caignard DH, Atassi G. Kostakis I, et al. Farmaco. 2000 Jun-Jul;55(6-7):455-60. doi: 10.1016/s0014-827x(00)00068-9. Farmaco. 2000. PMID: 11204746

3

Synthesis, cytotoxic activity, NMR study and stereochemical effects of some new pyrano[3,2-b]thioxanthen-6-ones and pyrano[2,3-c]thioxanthen-7-ones.

Kostakis IK, Pouli N, Marakos P, Mikros E, Skaltsounis AL, Leonce S, Atassi G, Renard P. Kostakis IK, et al. Bioorg Med Chem. 2001 Nov;9(11):2793-802. doi: 10.1016/s0968-0896(01)00130-4. Bioorg Med Chem. 2001. PMID: 11597459

4

Design and synthesis of some new pyranoxanthenone aminoderivatives with cytotoxic activity.

Kolokythas G, Kostakis IK, Pouli N, Marakos P, Skaltsounis AL, Pratsinis H. Kolokythas G, et al. Among authors: kostakis ik. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1443-6. doi: 10.1016/s0960-894x(02)00218-4. Bioorg Med Chem Lett. 2002. PMID: 12031316

5

Design, synthesis, and antiproliferative activity of some new pyrazole-fused amino derivatives of the pyranoxanthenone, pyranothioxanthenone, and pyranoacridone ring systems: a new class of cytotoxic agents.

Kostakis IK, Magiatis P, Pouli N, Marakos P, Skaltsounis AL, Pratsinis H, Léonce S, Pierré A. Kostakis IK, et al. J Med Chem. 2002 Jun 6;45(12):2599-609. doi: 10.1021/jm011117g. J Med Chem. 2002. PMID: 12036369

6

Synthesis and cytotoxic activity of some new azapyranoxanthenone aminoderivatives.

Kolokythas G, Kostakis IK, Pouli N, Marakos P, Kletsas D, Pratsinis H. Kolokythas G, et al. Among authors: kostakis ik. Bioorg Med Chem. 2003 Oct 15;11(21):4591-8. doi: 10.1016/s0968-0896(03)00503-0. Bioorg Med Chem. 2003. PMID: 14527556

7

Design, synthesis, and antiproliferative activity of some novel aminosubstituted xanthenones, able to overcome multidrug resistance toward MES-SA/Dx5 cells.

Kostakis IK, Tenta R, Pouli N, Marakos P, Skaltsounis AL, Pratsinis H, Kletsas D. Kostakis IK, et al. Bioorg Med Chem Lett. 2005 Nov 15;15(22):5057-60. doi: 10.1016/j.bmcl.2005.07.079. Bioorg Med Chem Lett. 2005. PMID: 16169719

8

Design and synthesis of novel amino-substituted xanthenones and benzo[b]xanthenones: evaluation of their antiproliferative activity and their ability to overcome multidrug resistance toward MES-SA/D x 5 cells.

Kostakis IK, Pouli N, Marakos P, Skaltsounis AL, Pratsinis H, Kletsas D. Kostakis IK, et al. Bioorg Med Chem. 2006 May 1;14(9):2910-34. doi: 10.1016/j.bmc.2005.12.003. Epub 2006 Jan 11. Bioorg Med Chem. 2006. PMID: 16376546

9

Antiproliferative and proapoptotic activities of pyranoxanthenones, pyranothioxanthenones and their pyrazole-fused derivatives in HL-60 cells.

Perchellet EM, Ward MM, Skaltsounis AL, Kostakis IK, Pouli N, Marakos P, Perchellet JP. Perchellet EM, et al. Among authors: kostakis ik. Anticancer Res. 2006 Jul-Aug;26(4B):2791-804. Anticancer Res. 2006. PMID: 16886598 Free article.

10

Design and synthesis of new pyranoxanthenones bearing a nitro group or an aminosubstituted side chain on the pyran ring. Evaluation of their growth inhibitory activity in breast cancer cells.

Kolokythas G, Kostakis IK, Pouli N, Marakos P, Kousidou OCh, Tzanakakis GN, Karamanos NK. Kolokythas G, et al. Among authors: kostakis ik. Eur J Med Chem. 2007 Mar;42(3):307-19. doi: 10.1016/j.ejmech.2006.10.018. Epub 2006 Dec 4. Eur J Med Chem. 2007. PMID: 17145121

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