Luo J - Search Results

1

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism.

Engelman JA, Luo J, Cantley LC. Engelman JA, et al. Among authors: luo j. Nat Rev Genet. 2006 Aug;7(8):606-19. doi: 10.1038/nrg1879. Nat Rev Genet. 2006. PMID: 16847462 Review.

2

Targeting the PI3K-Akt pathway in human cancer: rationale and promise.

Luo J, Manning BD, Cantley LC. Luo J, et al. Cancer Cell. 2003 Oct;4(4):257-62. doi: 10.1016/s1535-6108(03)00248-4. Cancer Cell. 2003. PMID: 14585353 Free article. Review. No abstract available.

3

Synthesis and activity of C11-modified wortmannin probes for PI3 kinase.

Yuan H, Luo J, Field S, Weissleder R, Cantley L, Josephson L. Yuan H, et al. Among authors: luo j. Bioconjug Chem. 2005 May-Jun;16(3):669-75. doi: 10.1021/bc049714f. Bioconjug Chem. 2005. PMID: 15898736

4

Modulation of epithelial neoplasia and lymphoid hyperplasia in PTEN+/- mice by the p85 regulatory subunits of phosphoinositide 3-kinase.

Luo J, Sobkiw CL, Logsdon NM, Watt JM, Signoretti S, O'Connell F, Shin E, Shim Y, Pao L, Neel BG, Depinho RA, Loda M, Cantley LC. Luo J, et al. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10238-43. doi: 10.1073/pnas.0504378102. Epub 2005 Jul 8. Proc Natl Acad Sci U S A. 2005. PMID: 16006513 Free PMC article.

5

The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex.

Luo J, Field SJ, Lee JY, Engelman JA, Cantley LC. Luo J, et al. J Cell Biol. 2005 Aug 1;170(3):455-64. doi: 10.1083/jcb.200503088. Epub 2005 Jul 25. J Cell Biol. 2005. PMID: 16043515 Free PMC article.

6

The negative regulation of phosphoinositide 3-kinase signaling by p85 and it's implication in cancer.

Luo J, Cantley LC. Luo J, et al. Cell Cycle. 2005 Oct;4(10):1309-12. doi: 10.4161/cc.4.10.2062. Epub 2005 Oct 28. Cell Cycle. 2005. PMID: 16131837

7

Class IA phosphoinositide 3-kinase regulates heart size and physiological cardiac hypertrophy.

Luo J, McMullen JR, Sobkiw CL, Zhang L, Dorfman AL, Sherwood MC, Logsdon MN, Horner JW, DePinho RA, Izumo S, Cantley LC. Luo J, et al. Mol Cell Biol. 2005 Nov;25(21):9491-502. doi: 10.1128/MCB.25.21.9491-9502.2005. Mol Cell Biol. 2005. PMID: 16227599 Free PMC article.

8

Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells.

Isakoff SJ, Engelman JA, Irie HY, Luo J, Brachmann SM, Pearline RV, Cantley LC, Brugge JS. Isakoff SJ, et al. Among authors: luo j. Cancer Res. 2005 Dec 1;65(23):10992-1000. doi: 10.1158/0008-5472.CAN-05-2612. Cancer Res. 2005. PMID: 16322248

9

Wortmannin-C20 conjugates generate wortmannin.

Yuan H, Luo J, Weissleder R, Cantley L, Josephson L. Yuan H, et al. Among authors: luo j. J Med Chem. 2006 Jan 26;49(2):740-7. doi: 10.1021/jm050699p. J Med Chem. 2006. PMID: 16420059

10

Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta.

Taniguchi CM, Kondo T, Sajan M, Luo J, Bronson R, Asano T, Farese R, Cantley LC, Kahn CR. Taniguchi CM, et al. Among authors: luo j. Cell Metab. 2006 May;3(5):343-53. doi: 10.1016/j.cmet.2006.04.005. Cell Metab. 2006. PMID: 16679292 Free article.

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