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Immune adjuvant efficacy of CpG oligonucleotide in cancer treatment is founded specifically upon TLR9 function in plasmacytoid dendritic cells.
Nierkens S, den Brok MH, Garcia Z, Togher S, Wagenaars J, Wassink M, Boon L, Ruers TJ, Figdor CG, Schoenberger SP, Adema GJ, Janssen EM. Nierkens S, et al. Among authors: den brok mh. Cancer Res. 2011 Oct 15;71(20):6428-37. doi: 10.1158/0008-5472.CAN-11-2154. Epub 2011 Jul 25. Cancer Res. 2011. PMID: 21788345 Free PMC article.
Tumor ablation plus co-administration of CpG and saponin adjuvants affects IL-1 production and multifunctional T cell numbers in tumor draining lymph nodes.
Raaijmakers TK, van den Bijgaart RJE, den Brok MH, Wassink M, de Graaf A, Wagenaars JA, Nierkens S, Ansems M, Scheffer GJ, Adema GJ. Raaijmakers TK, et al. Among authors: den brok mh. J Immunother Cancer. 2020 May;8(1):e000649. doi: 10.1136/jitc-2020-000649. J Immunother Cancer. 2020. PMID: 32461350 Free PMC article.
Dendritic cells: tools and targets for antitumor vaccination.
den Brok MH, Nierkens S, Figdor CG, Ruers TJ, Adema GJ. den Brok MH, et al. Expert Rev Vaccines. 2005 Oct;4(5):699-710. doi: 10.1586/14760584.4.5.699. Expert Rev Vaccines. 2005. PMID: 16221071 Free article. Review.
40 results