Sun Y - Search Results

1

Conditional expression of human acid beta-glucosidase improves the visceral phenotype in a Gaucher disease mouse model.

Sun Y, Quinn B, Xu YH, Leonova T, Witte DP, Grabowski GA. Sun Y, et al. J Lipid Res. 2006 Oct;47(10):2161-70. doi: 10.1194/jlr.M600239-JLR200. Epub 2006 Jul 21. J Lipid Res. 2006. PMID: 16861620 Free article.

2

Ex vivo localization of the mouse saposin C activation region for acid beta-glucosidase.

Qi X, Kondoh K, Yin H, Wang M, Ponce E, Sun Y, Grabowski GA. Qi X, et al. Among authors: sun y. Mol Genet Metab. 2002 Jul;76(3):189-200. doi: 10.1016/s1096-7192(02)00040-9. Mol Genet Metab. 2002. PMID: 12126932

3

Prosaposin: threshold rescue and analysis of the "neuritogenic" region in transgenic mice.

Sun Y, Qi X, Witte DP, Ponce E, Kondoh K, Quinn B, Grabowski GA. Sun Y, et al. Mol Genet Metab. 2002 Aug;76(4):271-86. doi: 10.1016/s1096-7192(02)00114-2. Mol Genet Metab. 2002. PMID: 12208132

4

Analyses of temporal regulatory elements of the prosaposin gene in transgenic mice.

Sun Y, Witte DP, Jin P, Grabowski GA. Sun Y, et al. Biochem J. 2003 Mar 1;370(Pt 2):557-66. doi: 10.1042/BJ20021120. Biochem J. 2003. PMID: 12467496 Free PMC article.

5

Saposin C is required for normal resistance of acid beta-glucosidase to proteolytic degradation.

Sun Y, Qi X, Grabowski GA. Sun Y, et al. J Biol Chem. 2003 Aug 22;278(34):31918-23. doi: 10.1074/jbc.M302752200. Epub 2003 Jun 17. J Biol Chem. 2003. PMID: 12813057 Free article.

6

Gaucher disease mouse models: point mutations at the acid beta-glucosidase locus combined with low-level prosaposin expression lead to disease variants.

Sun Y, Quinn B, Witte DP, Grabowski GA. Sun Y, et al. J Lipid Res. 2005 Oct;46(10):2102-13. doi: 10.1194/jlr.M500202-JLR200. Epub 2005 Aug 1. J Lipid Res. 2005. PMID: 16061944 Free article.

7

Saposin C: neuronal effect and CNS delivery by liposomes.

Chu Z, Sun Y, Kuan CY, Grabowski GA, Qi X. Chu Z, et al. Among authors: sun y. Ann N Y Acad Sci. 2005 Aug;1053:237-46. doi: 10.1196/annals.1344.021. Ann N Y Acad Sci. 2005. PMID: 16179529

8

Combined saposin C and D deficiencies in mice lead to a neuronopathic phenotype, glucosylceramide and alpha-hydroxy ceramide accumulation, and altered prosaposin trafficking.

Sun Y, Witte DP, Zamzow M, Ran H, Quinn B, Matsuda J, Grabowski GA. Sun Y, et al. Hum Mol Genet. 2007 Apr 15;16(8):957-71. doi: 10.1093/hmg/ddm040. Epub 2007 Mar 12. Hum Mol Genet. 2007. PMID: 17353235

9

Neurological deficits and glycosphingolipid accumulation in saposin B deficient mice.

Sun Y, Witte DP, Ran H, Zamzow M, Barnes S, Cheng H, Han X, Williams MT, Skelton MR, Vorhees CV, Grabowski GA. Sun Y, et al. Hum Mol Genet. 2008 Aug 1;17(15):2345-56. doi: 10.1093/hmg/ddn135. Epub 2008 May 14. Hum Mol Genet. 2008. PMID: 18480170 Free PMC article.

10

Temporal gene expression profiling reveals CEBPD as a candidate regulator of brain disease in prosaposin deficient mice.

Sun Y, Jia L, Williams MT, Zamzow M, Ran H, Quinn B, Aronow BJ, Vorhees CV, Witte DP, Grabowski GA. Sun Y, et al. BMC Neurosci. 2008 Aug 1;9:76. doi: 10.1186/1471-2202-9-76. BMC Neurosci. 2008. PMID: 18673548 Free PMC article.

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