Warshakoon NC - Search Results

1

Design and synthesis of substituted quinolines as novel and selective melanin concentrating hormone antagonists as anti-obesity agents.

Warshakoon NC, Sheville J, Bhatt RT, Ji W, Mendez-Andino JL, Meyers KM, Kim N, Wos JA, Mitchell C, Paris JL, Pinney BB, Reizes O, Hu XE. Warshakoon NC, et al. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5207-11. doi: 10.1016/j.bmcl.2006.07.006. Epub 2006 Jul 25. Bioorg Med Chem Lett. 2006. PMID: 16870427

2

Identification of substituted 4-aminopiperidines and 3-aminopyrrolidines as potent MCH-R1 antagonists for the treatment of obesity.

Kim N, Meyers KM, Mendez-Andino JL, Warshakoon NC, Ji W, Wos JA, Colson A, Mitchell MC, Davis JR, Pinney BB, Reizes O, Hu XE. Kim N, et al. Among authors: warshakoon nc. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5445-50. doi: 10.1016/j.bmcl.2006.07.053. Epub 2006 Aug 1. Bioorg Med Chem Lett. 2006. PMID: 16879961

3

Design and synthesis of substituted pyridine derivatives as HIF-1alpha prolyl hydroxylase inhibitors.

Warshakoon NC, Wu S, Boyer A, Kawamoto R, Sheville J, Bhatt RT, Renock S, Xu K, Pokross M, Zhou S, Walter R, Mekel M, Evdokimov AG, East S. Warshakoon NC, et al. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5616-20. doi: 10.1016/j.bmcl.2006.08.026. Bioorg Med Chem Lett. 2006. PMID: 16908149

4

Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors.

Warshakoon NC, Wu S, Boyer A, Kawamoto R, Sheville J, Renock S, Xu K, Pokross M, Zhou S, Winter C, Walter R, Mekel M, Evdokimov AG. Warshakoon NC, et al. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5517-22. doi: 10.1016/j.bmcl.2006.08.040. Epub 2006 Aug 22. Bioorg Med Chem Lett. 2006. PMID: 16931007

5

Aminomethyl tetrahydronaphthalene ketopiperazine MCH-R1 antagonists--Increasing selectivity over hERG.

Meyers KM, Méndez-Andino JL, Colson AO, Warshakoon NC, Wos JA, Mitchell MC, Hodge KM, Howard JM, Ackley DC, Holbert JK, Mittelstadt SW, Dowty ME, Obringer CM, Reizes O, Hu XE. Meyers KM, et al. Among authors: warshakoon nc. Bioorg Med Chem Lett. 2007 Feb 1;17(3):819-22. doi: 10.1016/j.bmcl.2006.10.052. Epub 2006 Oct 25. Bioorg Med Chem Lett. 2007. PMID: 17107796

6

A novel series of imidazo[1,2-a]pyridine derivatives as HIF-1alpha prolyl hydroxylase inhibitors.

Warshakoon NC, Wu S, Boyer A, Kawamoto R, Sheville J, Renock S, Xu K, Pokross M, Evdokimov AG, Walter R, Mekel M. Warshakoon NC, et al. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5598-601. doi: 10.1016/j.bmcl.2006.08.089. Epub 2006 Sep 8. Bioorg Med Chem Lett. 2006. PMID: 16962772

7

Design and synthesis of a series of novel pyrazolopyridines as HIF-1alpha prolyl hydroxylase inhibitors.

Warshakoon NC, Wu S, Boyer A, Kawamoto R, Renock S, Xu K, Pokross M, Evdokimov AG, Zhou S, Winter C, Walter R, Mekel M. Warshakoon NC, et al. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5687-90. doi: 10.1016/j.bmcl.2006.08.017. Bioorg Med Chem Lett. 2006. PMID: 16908145

8

Chemoenzymatic asymmetric total synthesis of phosphodiesterase inhibitors: preparation of a polycyclic pyrazolo[3,4-d]pyrimidine from an acylnitroso Diels-Alder cycloadduct-derived aminocyclopentenol.

Jiang MX, Warshakoon NC, Miller MJ. Jiang MX, et al. Among authors: warshakoon nc. J Org Chem. 2005 Apr 1;70(7):2824-7. doi: 10.1021/jo0484070. J Org Chem. 2005. PMID: 15787579

9

Synthetic application of acylnitroso Diels-Alder derived aminocyclopentenols: total synthesis of (+)-streptazolin.

Li F, Warshakoon NC, Miller MJ. Li F, et al. Among authors: warshakoon nc. J Org Chem. 2004 Dec 10;69(25):8836-41. doi: 10.1021/jo048606j. J Org Chem. 2004. PMID: 15575765

10

A novel chromium(0)-promoted four-component cycloaddition reaction.

Rigby JH, Heap CR, Warshakoon NC, Heeg MJ. Rigby JH, et al. Among authors: warshakoon nc. Org Lett. 1999 Aug 12;1(3):507-8. doi: 10.1021/ol990687w. Org Lett. 1999. PMID: 10822590

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