Mufti GJ - Search Results

1

Histone deacetylase inhibitors (HDI) cause DNA damage in leukemia cells: a mechanism for leukemia-specific HDI-dependent apoptosis?

Gaymes TJ, Padua RA, Pla M, Orr S, Omidvar N, Chomienne C, Mufti GJ, Rassool FV. Gaymes TJ, et al. Among authors: mufti gj. Mol Cancer Res. 2006 Aug;4(8):563-73. doi: 10.1158/1541-7786.MCR-06-0111. Mol Cancer Res. 2006. PMID: 16877702

2

Increased error-prone NHEJ activity in myeloid leukemias is associated with DNA damage at sites that recruit key nonhomologous end-joining proteins.

Brady N, Gaymes TJ, Cheung M, Mufti GJ, Rassool FV. Brady N, et al. Among authors: mufti gj. Cancer Res. 2003 Apr 15;63(8):1798-805. Cancer Res. 2003. PMID: 12702565

3

Myeloid leukemias have increased activity of the nonhomologous end-joining pathway and concomitant DNA misrepair that is dependent on the Ku70/86 heterodimer.

Gaymes TJ, Mufti GJ, Rassool FV. Gaymes TJ, et al. Among authors: mufti gj. Cancer Res. 2002 May 15;62(10):2791-7. Cancer Res. 2002. PMID: 12019155

4

Constitutive DNA damage is linked to DNA replication abnormalities in Bloom's syndrome cells.

Rassool FV, North PS, Mufti GJ, Hickson ID. Rassool FV, et al. Among authors: mufti gj. Oncogene. 2003 Nov 27;22(54):8749-57. doi: 10.1038/sj.onc.1206970. Oncogene. 2003. PMID: 14647470

5

Reactive oxygen species, DNA damage, and error-prone repair: a model for genomic instability with progression in myeloid leukemia?

Rassool FV, Gaymes TJ, Omidvar N, Brady N, Beurlet S, Pla M, Reboul M, Lea N, Chomienne C, Thomas NS, Mufti GJ, Padua RA. Rassool FV, et al. Among authors: mufti gj. Cancer Res. 2007 Sep 15;67(18):8762-71. doi: 10.1158/0008-5472.CAN-06-4807. Cancer Res. 2007. PMID: 17875717

6

Chromosomal instability syndromes are sensitive to poly ADP-ribose polymerase inhibitors.

Gaymes TJ, Shall S, Farzaneh F, Mufti GJ. Gaymes TJ, et al. Among authors: mufti gj. Haematologica. 2008 Dec;93(12):1886-9. doi: 10.3324/haematol.13201. Epub 2008 Oct 6. Haematologica. 2008. PMID: 18838476 Free article.

7

Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes.

Gaymes TJ, Shall S, MacPherson LJ, Twine NA, Lea NC, Farzaneh F, Mufti GJ. Gaymes TJ, et al. Among authors: mufti gj. Haematologica. 2009 May;94(5):638-46. doi: 10.3324/haematol.2008.001933. Haematologica. 2009. PMID: 19407318 Free PMC article.

8

FLT3 and JAK2 Mutations in Acute Myeloid Leukemia Promote Interchromosomal Homologous Recombination and the Potential for Copy Neutral Loss of Heterozygosity.

Gaymes TJ, Mohamedali A, Eiliazadeh AL, Darling D, Mufti GJ. Gaymes TJ, et al. Among authors: mufti gj. Cancer Res. 2017 Apr 1;77(7):1697-1708. doi: 10.1158/0008-5472.CAN-16-1678. Epub 2017 Jan 20. Cancer Res. 2017. PMID: 28108507 Free article.

9

Increased error-prone non homologous DNA end-joining--a proposed mechanism of chromosomal instability in Bloom's syndrome.

Gaymes TJ, North PS, Brady N, Hickson ID, Mufti GJ, Rassool FV. Gaymes TJ, et al. Among authors: mufti gj. Oncogene. 2002 Apr 11;21(16):2525-33. doi: 10.1038/sj.onc.1205331. Oncogene. 2002. PMID: 11971187

10

Reducing MCM levels in human primary T cells during the G(0)-->G(1) transition causes genomic instability during the first cell cycle.

Orr SJ, Gaymes T, Ladon D, Chronis C, Czepulkowski B, Wang R, Mufti GJ, Marcotte EM, Thomas NS. Orr SJ, et al. Among authors: mufti gj. Oncogene. 2010 Jul 1;29(26):3803-14. doi: 10.1038/onc.2010.138. Epub 2010 May 3. Oncogene. 2010. PMID: 20440261 Free PMC article.

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