Vigushin DM - Search Results

1

In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography.

Leyton J, Alao JP, Da Costa M, Stavropoulou AV, Latigo JR, Perumal M, Pillai R, He Q, Atadja P, Lam EW, Workman P, Vigushin DM, Aboagye EO. Leyton J, et al. Among authors: vigushin dm. Cancer Res. 2006 Aug 1;66(15):7621-9. doi: 10.1158/0008-5472.CAN-05-3962. Cancer Res. 2006. PMID: 16885362

2

Histone deacetylase inhibitor trichostatin A represses estrogen receptor alpha-dependent transcription and promotes proteasomal degradation of cyclin D1 in human breast carcinoma cell lines.

Alao JP, Lam EW, Ali S, Buluwela L, Bordogna W, Lockey P, Varshochi R, Stavropoulou AV, Coombes RC, Vigushin DM. Alao JP, et al. Among authors: vigushin dm. Clin Cancer Res. 2004 Dec 1;10(23):8094-104. doi: 10.1158/1078-0432.CCR-04-1023. Clin Cancer Res. 2004. PMID: 15585645

3

Quantification of cellular proliferation in tumor and normal tissues of patients with breast cancer by [18F]fluorothymidine-positron emission tomography imaging: evaluation of analytical methods.

Kenny LM, Vigushin DM, Al-Nahhas A, Osman S, Luthra SK, Shousha S, Coombes RC, Aboagye EO. Kenny LM, et al. Among authors: vigushin dm. Cancer Res. 2005 Nov 1;65(21):10104-12. doi: 10.1158/0008-5472.CAN-04-4297. Cancer Res. 2005. PMID: 16267037

4

The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines.

Alao JP, Gamble SC, Stavropoulou AV, Pomeranz KM, Lam EW, Coombes RC, Vigushin DM. Alao JP, et al. Among authors: vigushin dm. Mol Cancer. 2006 Feb 17;5:7. doi: 10.1186/1476-4598-5-7. Mol Cancer. 2006. PMID: 16503970 Free PMC article.

5

Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells.

Alao JP, Stavropoulou AV, Lam EW, Coombes RC, Vigushin DM. Alao JP, et al. Among authors: vigushin dm. Mol Cancer. 2006 Feb 20;5:8. doi: 10.1186/1476-4598-5-8. Mol Cancer. 2006. PMID: 16504004 Free PMC article.

6

Imaging early changes in proliferation at 1 week post chemotherapy: a pilot study in breast cancer patients with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography.

Kenny L, Coombes RC, Vigushin DM, Al-Nahhas A, Shousha S, Aboagye EO. Kenny L, et al. Among authors: vigushin dm. Eur J Nucl Med Mol Imaging. 2007 Sep;34(9):1339-47. doi: 10.1007/s00259-007-0379-4. Epub 2007 Mar 2. Eur J Nucl Med Mol Imaging. 2007. PMID: 17333178

7

Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice.

Sanderson L, Taylor GW, Aboagye EO, Alao JP, Latigo JR, Coombes RC, Vigushin DM. Sanderson L, et al. Among authors: vigushin dm. Drug Metab Dispos. 2004 Oct;32(10):1132-8. doi: 10.1124/dmd.104.000638. Epub 2004 Jul 21. Drug Metab Dispos. 2004. PMID: 15269190

8

ICI182,780 induces p21Waf1 gene transcription through releasing histone deacetylase 1 and estrogen receptor alpha from Sp1 sites to induce cell cycle arrest in MCF-7 breast cancer cell line.

Varshochi R, Halim F, Sunters A, Alao JP, Madureira PA, Hart SM, Ali S, Vigushin DM, Coombes RC, Lam EW. Varshochi R, et al. Among authors: vigushin dm. J Biol Chem. 2005 Feb 4;280(5):3185-96. doi: 10.1074/jbc.M408063200. Epub 2004 Nov 19. J Biol Chem. 2005. PMID: 15557281 Free article.

9

Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo.

Vigushin DM, Ali S, Pace PE, Mirsaidi N, Ito K, Adcock I, Coombes RC. Vigushin DM, et al. Clin Cancer Res. 2001 Apr;7(4):971-6. Clin Cancer Res. 2001. PMID: 11309348

10

Histone deacetylase inhibitors in cancer treatment.

Vigushin DM, Coombes RC. Vigushin DM, et al. Anticancer Drugs. 2002 Jan;13(1):1-13. doi: 10.1097/00001813-200201000-00001. Anticancer Drugs. 2002. PMID: 11914636 Review.

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